Kelly P Williams
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Explore the profile of Kelly P Williams including associated specialties, affiliations and a list of published articles.
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60
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3717
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Recent Articles
1.
Lado P, Crispell G, Chong S, Kim M, Esparza A, Zielinski E, et al.
Pathogens
. 2024 Aug;
13(8).
PMID: 39204305
Japanese encephalitis is a disease caused by the Japanese encephalitis virus (JEV) and is a concern for U.S. military personnel stationed in the Republic of Korea (ROK). The recent literature...
2.
Yu S, Mageeney C, Shormin F, Ghaffari N, Williams K
PLoS One
. 2024 Mar;
19(3):e0298641.
PMID: 38478526
Background: Genomic islands (GIs) are mobile genetic elements that integrate site-specifically into bacterial chromosomes, bearing genes that affect phenotypes such as pathogenicity and metabolism. GIs typically occur sporadically among related...
3.
Shen C, Liu B, Williams K, Warnow T
Algorithms Mol Biol
. 2023 Dec;
18(1):21.
PMID: 38062452
Background: Adding sequences into an existing (possibly user-provided) alignment has multiple applications, including updating a large alignment with new data, adding sequences into a constraint alignment constructed using biological knowledge,...
4.
Humphrey B, MacKenzie M, Lobitz M, Schambach J, Lasley G, Kolker S, et al.
Front Microbiol
. 2023 Nov;
14:1271836.
PMID: 37920264
The natural assemblage of a symbiotic bacterial microbiome (bacteriome) with microalgae in marine ecosystems is now being investigated as a means to increase algal productivity for industry. When algae are...
5.
Tommasini D, Mageeney C, Williams K
NAR Genom Bioinform
. 2023 Apr;
5(2):lqad036.
PMID: 37081865
Satellites such as phage-induced chromosomal islands (PICIs) are mobile genetic elements relying on helper phages for their mobilization, through trans-regulatory interactions. We discovered a PICI with a more intimate regulatory...
6.
Vuong I, Mageeney C, Williams K
Phage (New Rochelle)
. 2023 Feb;
3(4):213-220.
PMID: 36793884
Background: Gibson assembly and assembly-in-yeast are strategies to create long synthetic DNAs from diverse fragments, for example, when engineering bacteriophage genomes. Design for these methods requires terminal sequence overlaps in...
7.
Aiosa N, Sinha A, Albataineh H, Phillips A, Mageeney C, Wilde D, et al.
Chembiochem
. 2023 Feb;
24(7):e202200802.
PMID: 36734186
The emergence of drug-resistant pathogens necessitates the development of new countermeasures. In this regard, the introduction of probiotics to directly attack or competitively exclude pathogens presents a useful strategy. Application...
8.
Mageeney C, Trubl G, Williams K
Front Bioinform
. 2022 Oct;
2:866850.
PMID: 36304297
The mobilome of a microbe, i.e., its set of mobile elements, has major effects on its ecology, and is important to delineate properly in each genome. This becomes more challenging...
9.
Podlevsky J, Hudson C, Timlin J, Williams K
NAR Genom Bioinform
. 2021 Feb;
2(3):lqaa063.
PMID: 33575613
CRISPR arrays and CRISPR-associated (Cas) proteins comprise a widespread adaptive immune system in bacteria and archaea. These systems function as a defense against exogenous parasitic mobile genetic elements that include...
10.
Mageeney C, Sinha A, Mosesso R, Medlin D, Lau B, Rokes A, et al.
mSystems
. 2020 Aug;
5(4).
PMID: 32788409
New therapies are necessary to combat increasingly antibiotic-resistant bacterial pathogens. We have developed a technology platform of computational, molecular biology, and microbiology tools which together enable on-demand production of phages...