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Kelly Jin

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Articles 12
Citations 256
Followers 0
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Recent Articles
1.
Hunker A, Mich J, Taskin N, Torkelson A, Pham T, Bertagnolli D, et al.
bioRxiv . 2025 Jan; PMID: 39868122
-acting regulatory enhancer elements are valuable tools for gaining cell type-specific genetic access. Leveraging large chromatin accessibility atlases, putative enhancer sequences can be identified and deployed in adeno-associated virus (AAV)...
2.
Jin K, Yao Z, van Velthoven C, Kaplan E, Glattfelder K, Barlow S, et al.
Nature . 2025 Jan; 638(8049):182-196. PMID: 39743592
Biological ageing can be defined as a gradual loss of homeostasis across various aspects of molecular and cellular function. Mammalian brains consist of thousands of cell types, which may be...
3.
Jin K, McCoy B, Goldman E, Usova V, Tkachev V, Chitsazan A, et al.
Aging Cell . 2024 Jan; 23(4):e14079. PMID: 38263575
Across mammals, the epigenome is highly predictive of chronological age. These "epigenetic clocks," most of which have been built using DNA methylation (DNAm) profiles, have gained traction as biomarkers of...
4.
Jin K, Yao Z, van Velthoven C, Kaplan E, Glattfelder K, Barlow S, et al.
bioRxiv . 2024 Jan; PMID: 38168182
Biological aging can be defined as a gradual loss of homeostasis across various aspects of molecular and cellular function. Aging is a complex and dynamic process which influences distinct cell...
5.
Yao Z, van Velthoven C, Kunst M, Zhang M, McMillen D, Lee C, et al.
Nature . 2023 Dec; 624(7991):317-332. PMID: 38092916
The mammalian brain consists of millions to billions of cells that are organized into many cell types with specific spatial distribution patterns and structural and functional properties. Here we report...
6.
McCoy B, Brassington L, Jin K, Dolby G, Shrager S, Collins D, et al.
Evol Med Public Health . 2023 Jun; 11(1):187-201. PMID: 37388194
Exposure to social environmental adversity is associated with health and survival across many social species, including humans. However, little is known about how these health and mortality effects vary across...
7.
Yao Z, van Velthoven C, Kunst M, Zhang M, McMillen D, Lee C, et al.
bioRxiv . 2023 Apr; PMID: 37034735
The mammalian brain is composed of millions to billions of cells that are organized into numerous cell types with specific spatial distribution patterns and structural and functional properties. An essential...
8.
Jin K, Wilson K, Beck J, Nelson C, Brownridge 3rd G, Harrison B, et al.
PLoS Genet . 2022 Apr; 18(4):e1010199. PMID: 35476679
[This corrects the article DOI: 10.1371/journal.pgen.1008835.].
9.
Hilsabeck T, Liu-Bryan R, Guo T, Wilson K, Bose N, Raftery D, et al.
Geroscience . 2022 Apr; 44(4):2195-2211. PMID: 35381951
Elevated serum urate (hyperuricemia) promotes crystalline monosodium urate tissue deposits and gout, with associated inflammation and increased mortality. To identify modifiers of uric acid pathologies, we performed a fly Genome-Wide...
10.
Jin K, Wilson K, Beck J, Nelson C, Brownridge 3rd G, Harrison B, et al.
PLoS Genet . 2020 Jul; 16(7):e1008835. PMID: 32644988
In most organisms, dietary restriction (DR) increases lifespan. However, several studies have found that genotypes within the same species vary widely in how they respond to DR. To explore the...