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Kelly E Nissen

Explore the profile of Kelly E Nissen including associated specialties, affiliations and a list of published articles. Areas
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Citations 37
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Recent Articles
1.
Antoine M, Patrick K, Soret J, Duc P, Rage F, Cacciottolo R, et al.
iScience . 2020 Jan; 23(1):100809. PMID: 31927482
Spinal muscular atrophy (SMA) is a devastating motor neuron disorder caused by mutations in the survival motor neuron (SMN) gene. It remains unclear how SMN deficiency leads to the loss...
2.
Nissen K, Homer C, Ryan C, Shales M, Krogan N, Patrick K, et al.
Genes Dev . 2017 Apr; 31(7):688-701. PMID: 28446597
Multiple lines of evidence implicate chromatin in the regulation of premessenger RNA (pre-mRNA) splicing. However, the influence of chromatin factors on cotranscriptional splice site usage remains unclear. Here we investigated...
3.
Patrick K, Ryan C, Xu J, Lipp J, Nissen K, Roguev A, et al.
PLoS Genet . 2015 Apr; 11(3):e1005074. PMID: 25825871
Although numerous regulatory connections between pre-mRNA splicing and chromatin have been demonstrated, the precise mechanisms by which chromatin factors influence spliceosome assembly and/or catalysis remain unclear. To probe the genetic...