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Kellianne D Alexander

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Recent Articles
1.
Clark K, White A, Paslawski W, Alexander K, Peng S, Young-Pearse T, et al.
Mol Biol Cell . 2025 Jan; 36(2):br4. PMID: 39745872
Parkinson disease (PD) is the second most common neurodegenerative disease, characterized by both motor and cognitive features. Motor symptoms primarily involve midbrain dopaminergic neurons, while cognitive dysfunction involves cortical neurons....
2.
Liu S, Alexander K, Francis M
J Dev Biol . 2024 Oct; 12(4). PMID: 39449319
As nervous systems mature, neural circuit connections are reorganized to optimize the performance of specific functions in adults. This reorganization of connections is achieved through a remarkably conserved phase of...
3.
White A, Clark K, Alexander K, Ramalingam N, Young-Pearse T, Dettmer U, et al.
NPJ Parkinsons Dis . 2024 May; 10(1):107. PMID: 38773105
Alpha-synuclein (αS)-rich Lewy bodies and neurites in the cerebral cortex correlate with the presence of dementia in Parkinson disease (PD) and Dementia with Lewy bodies (DLB), but whether αS influences...
4.
Alexander K, Ramachandran S, Biswas K, Lambert C, Russell J, Oliver D, et al.
Nat Commun . 2023 Nov; 14(1):7520. PMID: 37980357
The elimination of synapses during circuit remodeling is critical for brain maturation; however, the molecular mechanisms directing synapse elimination and its timing remain elusive. We show that the transcriptional regulator...