Keito Hoshitsuki
Overview
Explore the profile of Keito Hoshitsuki including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
392
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0
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Recent Articles
11.
Mcdermott J, Wolf J, Hoshitsuki K, Huddart R, Caudle K, Whirl-Carrillo M, et al.
Clin Pharmacol Ther
. 2021 May;
111(2):366-372.
PMID: 34032273
Aminoglycosides are widely used antibiotics with notable side effects, such as nephrotoxicity, vestibulotoxicity, and sensorineural hearing loss (cochleotoxicity). MT-RNR1 is a gene that encodes the 12s rRNA subunit and is...
12.
Hoshitsuki K, Rathod S, Ramsey M, Zhu L, Moreland L, Fernandez C
J Pharmacol Exp Ther
. 2020 Oct;
375(3):488-497.
PMID: 33008870
Patients with rheumatoid arthritis (RA) are frequently treated with anti-tumor necrosis factor- immunoglobulin therapy but develop neutralizing antibodies against these drugs, necessitating therapeutic monitoring of drug concentrations and anti-drug antibodies....
13.
Nishii R, Baskin-Doerfler R, Yang W, Oak N, Zhao X, Yang W, et al.
Blood
. 2020 Jul;
137(3):364-373.
PMID: 32693409
There is growing evidence supporting an inherited basis for susceptibility to acute lymphoblastic leukemia (ALL) in children. In particular, we and others reported recurrent germline ETV6 variants linked to ALL...
14.
Hoshitsuki K, Molinelli A, Inaba H, Rubnitz J, Barker P
Clin Chem
. 2020 Apr;
66(4):518-522.
PMID: 32232459
No abstract available.
15.
Suiter C, Moriyama T, Matreyek K, Yang W, Scaletti E, Nishii R, et al.
Proc Natl Acad Sci U S A
. 2020 Feb;
117(10):5394-5401.
PMID: 32094176
As a prototype of genomics-guided precision medicine, individualized thiopurine dosing based on pharmacogenetics is a highly effective way to mitigate hematopoietic toxicity of this class of drugs. Recently, deficiency was...
16.
Hoshitsuki K, Crews K, Yang W, Smith C, Hankins J, Turner A, et al.
Genet Med
. 2019 Jul;
22(1):232-233.
PMID: 31341243
No abstract available.
17.
Fuhrman D, Crowley K, Vetterly C, Hoshitsuki K, Koval A, Carcillo J
J Pediatr Intensive Care
. 2019 May;
7(2):69-74.
PMID: 31073473
In this prospective observational study, we explored the association of daily fluid intake from medication use with fluid overload in 75 children beginning 24 hours after intubation. The mean percent...
18.
Jha R, Molyneaux B, Jackson T, Wallisch J, Park S, Poloyac S, et al.
J Neurotrauma
. 2018 Apr;
35(17):2125-2135.
PMID: 29648981
Cerebral edema is critical to morbidity/mortality in traumatic brain injury (TBI) and is worsened by hypotension. Glibenclamide may reduce cerebral edema by inhibiting sulfonylurea receptor-1 (Sur1); its effect on diffuse...
19.
Moriyama T, Nishii R, Perez-Andreu V, Yang W, Klussmann F, Zhao X, et al.
Nat Genet
. 2016 Feb;
48(4):367-73.
PMID: 26878724
Widely used as anticancer and immunosuppressive agents, thiopurines have narrow therapeutic indices owing to frequent toxicities, partly explained by TPMT genetic polymorphisms. Recent studies identified germline NUDT15 variation as another...