Keith R Matthews
Overview
Explore the profile of Keith R Matthews including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
78
Citations
1824
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Rojas F, Cayla M, Matthews K
PLoS Negl Trop Dis
. 2021 Apr;
15(4):e0009284.
PMID: 33909626
The ability to reproduce the developmental events of trypanosomes that occur in their mammalian host in vitro offers significant potential to assist in understanding of the underlying biology of the...
22.
Briggs E, Warren F, Matthews K, McCulloch R, Otto T
Parasitology
. 2021 Mar;
148(10):1223-1236.
PMID: 33678213
Kinetoplastid parasites are responsible for both human and animal diseases across the globe where they have a great impact on health and economic well-being. Many species and life cycle stages...
23.
Cayla M, Matthews K, Ivens A
Wellcome Open Res
. 2020 Dec;
5:219.
PMID: 33274300
Low-complexity regions (LCRs) on proteins have attracted increasing attention recently due to their role in the assembly of membraneless organelles or granules by liquid-liquid phase separation. Several examples of such...
24.
Szoor B, Silvester E, Matthews K
Trends Parasitol
. 2020 Feb;
36(3):266-278.
PMID: 32014419
African trypanosomes are mainly transmitted by tsetse flies. In recent years there has been good progress in understanding how the parasites prepare for transmission, detect their changed environment through the...
25.
McWilliam K, Ivens A, Morrison L, Mugnier M, Matthews K
Proc Natl Acad Sci U S A
. 2019 Oct;
116(45):22774-22782.
PMID: 31636179
African trypanosomes use an extreme form of antigenic variation to evade host immunity, involving the switching of expressed variant surface glycoproteins by a stochastic and parasite-intrinsic process. Parasite development in...
26.
Rojas F, Matthews K
Curr Opin Microbiol
. 2019 Aug;
52:124-129.
PMID: 31442903
Many microbial eukaryotes exhibit cell-cell communication to co-ordinate group behaviours as a strategy to exploit a changed environment, adapt to adverse conditions or regulate developmental responses. Although best characterised in...
27.
Szoor B, Simon D, Rojas F, Young J, Robinson D, Kruger T, et al.
mBio
. 2019 Jul;
10(4).
PMID: 31289175
Glycosomes are peroxisome-related organelles that compartmentalize the glycolytic enzymes in kinetoplastid parasites. These organelles are developmentally regulated in their number and composition, allowing metabolic adaptation to the parasite's needs in...
28.
Cayla M, Rojas F, Silvester E, Venter F, Matthews K
Parasit Vectors
. 2019 May;
12(1):190.
PMID: 31036044
African trypanosomes cause human African trypanosomiasis and animal African trypanosomiasis. They are transmitted by tsetse flies in sub-Saharan Africa. Although most famous for their mechanisms of immune evasion by antigenic...
29.
Rojas F, Silvester E, Young J, Milne R, Tettey M, Houston D, et al.
Cell
. 2018 Dec;
176(1-2):306-317.e16.
PMID: 30503212
Trypanosome parasites control their virulence and spread by using quorum sensing (QS) to generate transmissible "stumpy forms" in their host bloodstream. However, the QS signal "stumpy induction factor" (SIF) and...
30.
Silvester E, Ivens A, Matthews K
PLoS Negl Trop Dis
. 2018 Oct;
12(10):e0006863.
PMID: 30307943
In the bloodstream of mammalian hosts Trypanosoma brucei undergoes well-characterised density-dependent growth control and developmental adaptation for transmission. This involves the differentiation from proliferative, morphologically 'slender' forms to quiescent 'stumpy'...