Keith Haynes
Overview
Explore the profile of Keith Haynes including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
34
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0
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Recent Articles
1.
Hampton C, Sitaula S, Billon C, Haynes K, Avdagic A, Wanninayake U, et al.
Eur J Med Chem
. 2023 Jul;
258:115582.
PMID: 37421886
Estrogen-related receptors (ERR) are an orphan nuclear receptor sub-family that play a critical role in regulating gene transcription for several physiological processes including mitochondrial function, cellular energy utilization and homeostasis....
2.
Bush K, Corsi G, Yan A, Haynes K, Layzer J, Zhou J, et al.
Cell Chem Biol
. 2023 Jun;
30(8):879-892.e5.
PMID: 37390831
CRISPR-based editing has revolutionized genome engineering despite the observation that many DNA sequences remain challenging to target. Unproductive interactions formed between the single guide RNA's (sgRNA) Cas9-binding scaffold domain and...
3.
DCunha N, Moniruzzaman M, Haynes K, Malloci G, Cooper C, Margiotta E, et al.
ACS Infect Dis
. 2021 Aug;
7(9):2650-2665.
PMID: 34379382
Antibiotic resistance poses an immediate and growing threat to human health. Multidrug efflux pumps are promising targets for overcoming antibiotic resistance with small-molecule therapeutics. Previously, we identified a diaminoquinoline acrylamide,...
4.
Mehla J, Malloci G, Mansbach R, Lopez C, Tsivkovski R, Haynes K, et al.
mBio
. 2021 Jan;
12(1).
PMID: 33468691
Antibiotic-resistant bacteria rapidly spread in clinical and natural environments and challenge our modern lifestyle. A major component of defense against antibiotics in Gram-negative bacteria is a drug permeation barrier created...
5.