Keith A Maggert
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Explore the profile of Keith A Maggert including associated specialties, affiliations and a list of published articles.
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22
Citations
1059
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Recent Articles
1.
Kindelay S, Maggert K
Genetics
. 2024 May;
227(3).
PMID: 38797870
The major loci for the large primary ribosomal RNA (rRNA) genes (35S rRNAs) exist as hundreds to thousands of tandem repeats in all organisms and dozens to hundreds in Drosophila....
2.
Bughio F, Maggert K
Proc Natl Acad Sci U S A
. 2022 Jun;
119(25):e2118796119.
PMID: 35704756
Position-effect variegation (PEV) results from the juxtaposition of euchromatic and heterochromatic components of eukaryotic genomes, silencing genes near the new euchromatin/heterochromatin junctions. Silencing is itself heritable through S phase, giving...
3.
Kindelay S, Maggert K
Semin Cell Dev Biol
. 2022 May;
136:38-48.
PMID: 35595601
The ribosomal DNA (rDNA) in Drosophila is found as two additive clusters of individual 35 S cistrons. The multiplicity of rDNA is essential to assure proper translational demands, but the...
4.
Bughio F, Huckell G, Maggert K
Proc Natl Acad Sci U S A
. 2019 Sep;
116(40):20043-20053.
PMID: 31527269
Position effect variegation (PEV) in results from new juxtapositions of euchromatic and heterochromatic chromosomal regions, and manifests as striking bimodal patterns of gene expression. The semirandom patterns of PEV, reflecting...
5.
Maggert K
Proc Natl Acad Sci U S A
. 2019 Aug;
116(36):17616-17618.
PMID: 31434787
No abstract available.
6.
Valori V, Tus K, Laukaitis C, Harris D, LeBeau L, Maggert K
Epigenetics
. 2019 Jul;
15(1-2):85-106.
PMID: 31352858
Chromatin-mediated silencing, including the formation of heterochromatin, silent chromosome territories, and repressed gene promoters, acts to stabilize patterns of gene regulation and the physical structure of the genome. Reduction of...
7.
Ji J, Tang X, Hu W, Maggert K, Rong Y
PLoS Genet
. 2019 May;
15(5):e1008169.
PMID: 31100062
The Pol32 protein is one of the universal subunits of DNA polymerase δ (Pol δ), which is responsible for genome replication in eukaryotic cells. Although the role of Pol32 in...
8.
Bughio F, Maggert K
Chromosome Res
. 2018 Dec;
27(1-2):19-30.
PMID: 30511202
Our goal is to draw a line-hypothetical in its totality but experimentally supported at each individual step-connecting the ribosomal DNA and the phenomenon of transgenerational epigenetic inheritance of induced phenotypes....
9.
Aldrich J, Maggert K
PLoS Genet
. 2015 Apr;
11(4):e1005148.
PMID: 25885886
Ribosomal RNA gene (rDNA) copy number variation modulates heterochromatin formation and influences the expression of a large fraction of the Drosophila genome. This discovery, along with the link between rDNA,...
10.
Deans C, Maggert K
Genetics
. 2015 Apr;
199(4):887-96.
PMID: 25855649
Interest in the field of epigenetics has increased rapidly over the last decade, with the term becoming more identifiable in biomedical research, scientific fields outside of the molecular sciences, such...