Keith A Boroevich
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Explore the profile of Keith A Boroevich including associated specialties, affiliations and a list of published articles.
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45
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2205
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Recent Articles
1.
Sharma A, Lopez Y, Jia S, Lysenko A, Boroevich K, Tsunoda T
Sci Rep
. 2024 Jun;
14(1):12851.
PMID: 38834670
Tabular data analysis is a critical task in various domains, enabling us to uncover valuable insights from structured datasets. While traditional machine learning methods can be used for feature engineering...
2.
Sharma A, Lysenko A, Jia S, Boroevich K, Tsunoda T
J Hum Genet
. 2024 Feb;
69(10):487-497.
PMID: 38424184
The field of omics, driven by advances in high-throughput sequencing, faces a data explosion. This abundance of data offers unprecedented opportunities for predictive modeling in precision medicine, but also presents...
3.
Jia S, Lysenko A, Boroevich K, Sharma A, Tsunoda T
Brief Bioinform
. 2023 Jul;
24(5).
PMID: 37523217
Annotation of cell-types is a critical step in the analysis of single-cell RNA sequencing (scRNA-seq) data that allows the study of heterogeneity across multiple cell populations. Currently, this is most...
4.
Hamba Y, Kamatani T, Miya F, Boroevich K, Tsunoda T
iScience
. 2023 May;
26(5):106640.
PMID: 37250307
Accumulating evidence indicates that long intergenic non-coding RNAs (lincRNAs) show more tissue-specific expression patterns than protein-coding genes (PCGs). However, although lincRNAs are subject to canonical transcriptional regulation like PCGs, the...
5.
Sharma A, Lysenko A, Boroevich K, Tsunoda T
Sci Rep
. 2023 Feb;
13(1):2483.
PMID: 36774402
Modern oncology offers a wide range of treatments and therefore choosing the best option for particular patient is very important for optimal outcome. Multi-omics profiling in combination with AI-based predictive...
6.
Rheinbay E, Nielsen M, Abascal F, Wala J, Shapira O, Tiao G, et al.
Nature
. 2023 Jan;
614(7948):E40.
PMID: 36697832
No abstract available.
7.
Matsuo H, Kamatani T, Hamba Y, Boroevich K, Tsunoda T
BMC Genomics
. 2022 May;
23(1):351.
PMID: 35525921
Background: Immune status in the tumor microenvironment is an important determinant of cancer progression and patient prognosis. Although a higher immune activity is often associated with a better prognosis, this...
8.
Sugawara T, Miya F, Ishikawa T, Lysenko A, Nishino J, Kamatani T, et al.
iScience
. 2022 Feb;
25(2):103740.
PMID: 35128352
Elimination of cancerous cells by the immune system is an important mechanism of protection from cancer, however, its effectiveness can be reduced owing to development of resistance and evasion. To...
9.
Sharma A, Lysenko A, Boroevich K, Vans E, Tsunoda T
Brief Bioinform
. 2021 Aug;
22(6).
PMID: 34368836
Artificial intelligence methods offer exciting new capabilities for the discovery of biological mechanisms from raw data because they are able to detect vastly more complex patterns of association that cannot...
10.
Shigemizu D, Akiyama S, Higaki S, Sugimoto T, Sakurai T, Boroevich K, et al.
Alzheimers Res Ther
. 2020 Nov;
12(1):145.
PMID: 33172501
Background: Mild cognitive impairment (MCI) is a precursor to Alzheimer's disease (AD), but not all MCI patients develop AD. Biomarkers for early detection of individuals at high risk for MCI-to-AD...