Kei Segawa
Overview
Explore the profile of Kei Segawa including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
15
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0
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Recent Articles
1.
Watanabe-Matsui M, Kadoya S, Segawa K, Shima H, Nakagawa T, Nagasawa Y, et al.
iScience
. 2025 Jan;
28(1):111529.
PMID: 39758820
Heme is known to bind to the intrinsically disordered region (IDR) to regulate protein function. The binding of heme to the IDR of transcription factor BACH2 promotes plasma cell differentiation,...
2.
Segawa K, Igarashi K, Murayama K
FEBS Lett
. 2022 Mar;
596(12):1576-1585.
PMID: 35302665
The function of the transcription factor BACH1 is regulated by heme binding to multiple Cys-Pro (CP) motifs within its intrinsically disordered regions. Here, biochemical analyses were conducted to reveal the...
3.
Segawa K, Watanabe-Matsui M, Tsuda K, Matsui T, Shirouzu M, Igarashi K, et al.
Eur Biophys J
. 2019 Apr;
48(4):361-369.
PMID: 30937482
Transcriptional repressor Bach1 plays an important role in antioxidant response. Bach1 function is regulated by heme binding to the four cysteine-proline (CP) motifs in Bach1, which leads to inhibition of...
4.
Segawa K, Watanabe-Matsui M, Matsui T, Igarashi K, Murayama K
Tohoku J Exp Med
. 2019 Mar;
247(3):153-159.
PMID: 30853683
Heme is one of the key factors involved in the oxidative stress response of cells. The transcriptional repressor Bach1 plays an important role in this response through its heme-binding activity....
5.
Role of p120-catenin in the morphological changes of endothelial cells exposed to fluid shear stress
Sakamoto N, Segawa K, Kanzaki M, Ohashi T, Sato M
Biochem Biophys Res Commun
. 2010 Jul;
398(3):426-32.
PMID: 20599710
p120-Catenin is known to play important roles in cell-cell adhesion stability by binding to cadherin and morphological changes of cells by regulating small RhoGTPase activities. Although the expression and binding...