Ke-Qian Yang
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Explore the profile of Ke-Qian Yang including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
136
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Recent Articles
1.
Liu C, Zhang B, Liu Y, Yang K, Liu S
ACS Synth Biol
. 2017 Nov;
7(2):591-601.
PMID: 29087704
The quantitative monitoring of intracellular metabolites with in vivo biosensors provides an efficient means of identifying high-yield strains and observing product accumulation in real time. In this study, a shikimic...
2.
Wu X, Tian X, Ji J, Wu W, Fan K, Yang K
Biotechnol Lett
. 2010 Dec;
33(4):805-12.
PMID: 21190060
Deacetoxy/deacetylcephalosporin C synthase (acDAOC/DACS) from Acremonium chrysogenum is a bifunctional enzyme that catalyzes both the ring-expansion of penicillin N to deacetoxycephalosporin C and the hydroxylation of the latter to deacetylcephalosporin...
3.
Xiang S, Li J, Yin H, Zheng J, Yang X, Wang H, et al.
Metab Eng
. 2009 Jul;
11(4-5):310-8.
PMID: 19584003
A reporter-guided mutant selection (RGMS) method has been developed wherein reporters are used to facilitate selection of target over-expressing mutants. It was applied to improve clavulanic acid (CA) production in...
4.
Fu D, Jiang W, Zheng J, Zhao G, Li Y, Yi H, et al.
Mol Cancer Ther
. 2008 Aug;
7(8):2386-93.
PMID: 18723485
Aurora kinases have emerged as promising targets for cancer therapy because of their critical role in mitosis. These kinases are well-conserved in all eukaryotes, and IPL1 gene encodes the single...
5.
Xu X, Wang Z, Fan K, Wang S, Jia C, Han H, et al.
FEMS Microbiol Lett
. 2008 Aug;
287(1):15-21.
PMID: 18691223
Structurally diverse polyketides provide a rich reservoir of bioactive molecules. Actinorhodin, a model aromatic polyketide, is synthesized by minimal type II polyketide synthase and tailoring enzymes. The ActIII actinorhodin ketoreductase...
6.
Wang S, Fan K, Yang X, Lin Z, Xu X, Yang K
J Bacteriol
. 2008 Apr;
190(11):4061-8.
PMID: 18375559
Ca(2+) was reported to regulate spore germination and aerial hypha formation in streptomycetes; the underlying mechanism of this regulation is not known. cabC, a gene encoding an EF-hand calcium-binding protein,...
7.
Yang K
Wei Sheng Wu Xue Bao
. 2008 Feb;
47(6):956-62.
PMID: 18271245
TPR repeat was originally defined as a 34 amino acid structural repeat (TPR-34). Equal length tandem repeats (ELTR) was proposed to represent the ancestral repeat pattern. Length polymorphism of TPR...
8.
Zheng J, Wang S, Yang K
Appl Microbiol Biotechnol
. 2007 Jul;
76(4):883-8.
PMID: 17653711
Streptomyces venezuelae ISP5230 produces a group of jadomycin congeners with cytotoxic activities. To improve jadomycin fermentation process, a genetic engineering strategy was designed to replace a 3.4-kb regulatory region of...
9.
Wang Z, Xu X, Fan K, Jia C, Yang K
J Biochem Biophys Methods
. 2007 Apr;
70(4):565-72.
PMID: 17399796
Ammonium sulfate precipitation was tested as a sample preparation step for BN-PAGE analyses of S. coelicolor cytoplasmic protein complexes. A procedure of sample preparation compatible with two-dimensional BN/SDS-PAGE was established...
10.
He Y, Fan K, Jia C, Wang Z, Pan W, Huang L, et al.
Appl Microbiol Biotechnol
. 2007 Jan;
75(2):367-76.
PMID: 17262208
A new gene encoding a thermostable Fe-superoxide dismutase (tcSOD) was identified from a metagenomic library prepared from a hot spring sample. The open reading frame of tcSOD encoded a 211...