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Kazunori Hoshino

Explore the profile of Kazunori Hoshino including associated specialties, affiliations and a list of published articles. Areas
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Articles 44
Citations 584
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Recent Articles
1.
Modarelli M, Kot-Thompson D, Hoshino K
Lab Chip . 2024 Dec; 25(2):127-142. PMID: 39676609
The gold standard of microfluidic fabrication techniques, SU-8 patterning, requires photolithography equipment and facilities and is not suitable for 3D microfluidics. A 3D printer is more convenient and may achieve...
2.
Cho S, Li W, Beard A, Jackson J, Kiernan R, Hoshino K, et al.
Proc Natl Acad Sci U S A . 2024 Sep; 121(39):e2407083121. PMID: 39292751
Ovulation is critical for sexual reproduction and consists of the process of liberating fertilizable oocytes from their somatic follicle capsules, also known as follicle rupture. The mechanical force for oocyte...
3.
Tomizawa Y, Wali K, Surti M, Suhail Y, Kshitiz , Hoshino K
bioRxiv . 2024 May; PMID: 38766194
Most common cytometry methods, including flow cytometry, observe suspended or fixed cells and cannot evaluate their structural roles in 3D tissues. However, cellular physical interactions are critical in physiological, developmental,...
4.
Vaish A, Tomizawa Y, Daggett D, Hoshino K
Ann Biomed Eng . 2023 Nov; 52(3):647-656. PMID: 38036895
The proper formation of the vertebrate embryonic heart relies on various mechanical forces which determine its form and function. Measuring these forces at the microscale of the embryo is a...
5.
Madhavan M, Jaiswal D, Karlberg S, Duggan A, Almarshad H, Claffey K, et al.
PLoS One . 2023 May; 18(5):e0286291. PMID: 37228139
Multicellular cancer spheroids are an in vitro tissue model that mimics the three-dimensional microenvironment. As spheroids grow, they develop the gradients of oxygen, nutrients, and catabolites, affecting crucial tumor characteristics...
6.
Tomizawa Y, Daggett D, Zheng G, Hoshino K
J Biophotonics . 2022 Nov; 16(3):e202200238. PMID: 36336921
We evaluated the elasticity of live tissues of zebrafish embryos using label-free optical elastography. We employed a pair of custom-built elastic microcantilevers to gently compress a zebrafish embryo and used...
7.
Moscato Z, Jaiswal D, Dixit K, Langanis C, Claffey K, Hoshino K
Methods Mol Biol . 2022 Jan; 2394:31-46. PMID: 35094320
By combining novel micro-scale manipulation cantilevers with commercially available, widely used 3D light microscopy, we were able to develop a new method of 3D elastography specialized for the analysis of...
8.
Alhudaithy S, Hoshino K
PLoS One . 2022 Jan; 17(1):e0262950. PMID: 35073389
This study presents novel biocompatible Polydimethylsiloxane (PDMS)-based micromechanical tweezers (μTweezers) capable of the stiffness characterization and manipulation of hydrogel-based organoids. The system showed great potential for complementing established mechanical characterization...
9.
Jiang S, Guo C, Bian Z, Wang R, Zhu J, Song P, et al.
Biosens Bioelectron . 2021 Oct; 196:113699. PMID: 34653716
Traditional microbial detection methods often rely on the overall property of microbial cultures and cannot resolve individual growth event at high spatiotemporal resolution. As a result, they require bacteria to...
10.
Jaiswal D, Tang-Schomer M, Sood D, Kaplan D, Hoshino K
ACS Biomater Sci Eng . 2021 Jan; 4(9):3259-3267. PMID: 33435062
We propose a novel nondestructive, label-free, mechanical characterization method for composite biomimetic materials. The method combines microscale-force measurement, bright-field microscopy based deformation analysis, and finite-element methods (FEM) to study the...