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Kazuki Kawahara

Explore the profile of Kazuki Kawahara including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 150
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Recent Articles
1.
Masuda R, Phyu Thant K, Kawahara K, Oki H, Kadonosono T, Kobayashi Y, et al.
J Biol Chem . 2024 Sep; 300(11):107794. PMID: 39305955
Many bioactive proteins interact with collagen, recognizing amino acid sequences displayed on the triple helix. We report here a selection strategy to obtain triple-helical peptides that interact with the proteins...
2.
Fujii S, Sakaguchi R, Oki H, Kawahara K, Ohkubo T, Fujiyoshi S, et al.
J Struct Biol . 2023 Sep; 215(4):108031. PMID: 37758155
Two homologous cytochromes c', SBCP and SVCP, from deep-sea Shewanella benthica and Shewanella violacea respectively exhibit only nine surface amino acid substitutions, along with one at the N-terminus. Despite the...
3.
Kusumi T, Katakami S, Ishikawa R, Kawahara K, Shibata N, Okada M
Ultramicroscopy . 2023 Jul; 253:113811. PMID: 37499573
In this study, we proposed a fast method of reconstruction for scanning transmission electron microscopy images. The proposed method is based on the Markov random field model and Bayesian inference,...
4.
Oki H, Kawahara K, Iimori M, Imoto Y, Nishiumi H, Maruno T, et al.
Sci Adv . 2022 Oct; 8(41):eabo3013. PMID: 36240278
Colonization of the host intestine is the most important step in infection. The toxin-coregulated pilus (TCP), an operon-encoded type IVb pilus (T4bP), plays a crucial role in this process, which...
5.
Yoshimi T, Fujii S, Oki H, Igawa T, Adams H, Ueda K, et al.
Acta Crystallogr F Struct Biol Commun . 2022 Jun; 78(Pt 6):217-225. PMID: 35647678
Cytochrome c'-β is a heme protein that belongs to the cytochrome P460 family and consists of homodimeric subunits with a predominantly antiparallel β-sheet fold. Here, the crystal structure of cytochrome...
6.
Ueda K, Kawahara K, Kimoto N, Yamaguchi Y, Yamada K, Oki H, et al.
BMC Genomics . 2022 Mar; 23(1):226. PMID: 35321661
Background: BEC-producing Clostridium perfringens is a causative agent of foodborne gastroenteritis. It was first reported in 2014, and since then, several isolates have been identified in Japan and the United...
7.
Shimamoto S, Nakagawa Y, Hidaka Y, Maruno T, Kobayashi Y, Kawahara K, et al.
Biochem Biophys Res Commun . 2021 Jul; 569:66-71. PMID: 34237429
Prostaglandin D (PGD), an endogenous somnogen, is a unique PG that is secreted into the cerebrospinal fluid. PGD is a relatively fragile molecule and should be transported to receptors localized...
8.
Kawahara K, Yoshida T, Maruno T, Oki H, Ohkubo T, Koide T, et al.
Proc Natl Acad Sci U S A . 2020 May; 117(21):11450-11458. PMID: 32385162
Dynamic remodeling of the extracellular matrix affects many cellular processes, either directly or indirectly, through the regulation of soluble ligands; however, the mechanistic details of this process remain largely unknown....
9.
Yoshida T, Oki H, Doi M, Fukuda S, Yuzuriha T, Tabata R, et al.
Sci Rep . 2020 May; 10(1):7623. PMID: 32376995
Small-molecule agonism of peroxisome proliferator-activated receptor α (PPARα), a ligand-activated transcriptional factor involved in regulating fatty acid metabolism, is an important approach for treating dyslipidemia. Here, we determined the structures...
10.
Suka A, Oki H, Kato Y, Kawahara K, Ohkubo T, Maruno T, et al.
Extremophiles . 2019 Jan; 23(2):239-248. PMID: 30689055
The stability of dimeric cytochrome c' from a thermophile, as compared with that of a homologous mesophilic counterpart, is attributed to strengthened interactions around the heme and at the subunit-subunit...