Kazufumi Kobayashi
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Explore the profile of Kazufumi Kobayashi including associated specialties, affiliations and a list of published articles.
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59
Citations
437
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Recent Articles
1.
Qiang N, Ao J, Nakamura M, Katayama K, Zhang J, Kogure T, et al.
Biochem Pharmacol
. 2025 Feb;
235:116829.
PMID: 40015652
Lenvatinib (LEN)-treated patients with hepatocellular carcinoma (HCC) are frequently accompanied by skeletal muscle loss, which is correlated with poor prognosis. Interactions between tumor and skeletal muscle may play a role...
2.
Ozaki T, Yumita S, Ogasawara S, Fujiya M, Tsuchiya T, Yoshino R, et al.
Hepatol Res
. 2024 Jun;
PMID: 38943555
Cytokine release syndrome (CRS) is a systemic inflammatory syndrome that causes fatal circulatory failure due to hypercytokinemia, and subsequent immune cell hyperactivation caused by therapeutic agents, pathogens, cancers, and autoimmune...
3.
Kobayashi K, Ogasawara S, Itobayashi E, Okubo T, Itokawa N, Nakamura K, et al.
Invest New Drugs
. 2024 Jun;
42(4):394-404.
PMID: 38842657
This study aimed to complement the results of the REACH-2 study by prospectively evaluating the safety and efficacy of ramucirumab in advanced hepatocellular carcinoma (HCC) in a real-world setting. This...
4.
Fujiwara K, Kondo T, Fujimoto K, Yumita S, Ogawa K, Ishino T, et al.
J Gastroenterol
. 2024 Apr;
59(6):515-525.
PMID: 38583112
Background: During systemic therapy, the management of portal hypertension (PH)-related complications is vital. This study aimed to clarify factors associated with the incidence and exacerbation of PH-related complications, including the...
5.
Yoshida R, Koroki K, Makishima H, Ogasawara S, Ishino T, Ogawa K, et al.
Case Rep Oncol
. 2023 Dec;
14(2):1103-1110.
PMID: 38075390
Macrovascular invasion (MVI), including portal vein tumor thrombosis (PVTT), is strongly associated with poor prognosis in patients with hepatocellular carcinoma (HCC). While recommended standard treatment for patients with advanced HCC...
6.
Kobayashi K, Ogasawara S, Maruta S, Okubo T, Itokawa N, Haga Y, et al.
Clin Cancer Res
. 2023 Oct;
29(23):4760-4769.
PMID: 37796614
Purpose: This study aimed to investigate the safety and efficacy of lenvatinib in real-world settings, including patients excluded from the REFLECT trial, a phase III trial that compared lenvatinib with...
7.
Kondo T, Fujimoto K, Fujiwara K, Yumita S, Ishino T, Ogawa K, et al.
Sci Rep
. 2023 Aug;
13(1):14043.
PMID: 37640752
The pathogenesis of acute liver failure (ALF) involves cell death. Necroptosis is a newly suggested programmed cell death, and receptor-interacting protein kinase 3 (RIPK3) has been reported as a marker...
8.
Kanzaki H, Ogasawara S, Okubo T, Itokawa N, Yoshino R, Fujimoto K, et al.
Drugs Real World Outcomes
. 2023 Jul;
10(4):513-520.
PMID: 37466822
Background: Cabozantinib was found to be effective as a second- or third-line treatment after sorafenib in patients with advanced hepatocellular carcinoma (HCC) in the phase 3 CELESTIAL trial. So far,...
9.
Kondo T, Fujiwara K, Nakagawa M, Fujimoto K, Yumita S, Ishino T, et al.
Sci Rep
. 2023 Jul;
13(1):11524.
PMID: 37460776
The effect of the combination of atezolizumab and bevacizumab (Atez/Bev) for hepatocellular carcinoma (HCC) on pulmonary arterial hypertension (PAH) is unknown. Estimation of PAH by using computed tomography (CT) has...
10.
Yumita S, Ogasawara S, Nakagawa M, Maruta S, Okubo T, Itokawa N, et al.
BMC Gastroenterol
. 2023 Apr;
23(1):101.
PMID: 37003980
Background: Hyperprogressive disease (HPD) is a phenomenon with greatly accelerated tumor growth and clinical deterioration rates compared to pre-therapy, in patients treated with immune checkpoint inhibitors (ICI). The aim of...