Kazue Tsuji-Takayama
Overview
Explore the profile of Kazue Tsuji-Takayama including associated specialties, affiliations and a list of published articles.
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15
Citations
170
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Recent Articles
1.
Masuda T, Hirata T, Sakamoto T, Tsubata Y, Ichihara E, Kozuki T, et al.
J Thorac Dis
. 2024 Jun;
16(5):3381-3388.
PMID: 38883673
Background: There is no established standard 3 line treatment for patients with advanced non-small cell lung cancer (NSCLC). Although cytotoxic chemotherapeutic agents that are not used as 1 or 2...
2.
Takemoto A, Takagi S, Ukaji T, Gyobu N, Kakino M, Takami M, et al.
Clin Cancer Res
. 2022 Apr;
28(12):2633-2645.
PMID: 35381070
Purpose: Osteosarcoma, the most common bone malignancy in children, has a poor prognosis, especially when the tumor metastasizes to the lungs. Therefore, novel therapeutic strategies targeting both proliferation and metastasis...
3.
Suzuki M, Takeuchi M, Tsuji-Takayama K, Harashima A, Otani T, Toraya T, et al.
Results Immunol
. 2013 Dec;
2:158-65.
PMID: 24371580
Nuclear receptors (NRs) have recently received much attention for their newly discovered roles in T cell development, as exemplified by RARα (Treg cells) and RORγt (Th17 cells). In previous studies,...
4.
Inoue T, Tashiro Y, Takeuchi M, Otani T, Tsuji-Takayama K, Okochi A, et al.
Int J Oncol
. 2011 Mar;
38(5):1299-306.
PMID: 21373756
The T cell line HOZOT has a unique FOXP3+CD4+ CD8+CD25+ phenotype, exhibits suppressive activity in allogeneic mixed lymphocyte reactions (MLR), and produces IL-10, defining HOZOT as regulatory T cells (Tregs)....
5.
Yamamoto M, Kondo E, Takeuchi M, Harashima A, Otani T, Tsuji-Takayama K, et al.
PLoS One
. 2011 Feb;
6(2):e16841.
PMID: 21304824
MicroRNAs (miRNAs) play important roles in regulating post-transcriptional gene repression in a variety of immunological processes. In particular, much attention has been focused on their roles in regulatory T (Treg)...
6.
Otani T, Tsuji-Takayama K, Okochi A, Yamamoto M, Takeuchi M, Yamasaki F, et al.
Immunol Cell Biol
. 2010 Jul;
89(2):246-54.
PMID: 20628373
We have previously shown that xenogeneic stromal cell stimulation of naïve T cells resulted in the generation of a new type of regulatory T (Treg) cell termed HOZOT, which has...
7.
Harashima A, Toraya T, Okochi A, Yamamoto M, Suzuki M, Otani T, et al.
Mol Immunol
. 2009 Aug;
46(16):3310-9.
PMID: 19699525
Distinct cytokine production profiles define the effector functions of both helper and regulatory T cells. Recently, we established novel cytotoxic regulatory T (Treg) cell lines, HOZOT, which have been characterized...
8.
Tsuji-Takayama K, Suzuki M, Yamamoto M, Harashima A, Okochi A, Otani T, et al.
J Immunol
. 2008 Sep;
181(6):3897-905.
PMID: 18768844
STAT5 molecules are key components of the IL-2 signaling pathway, the deficiency of which often results in autoimmune pathology due to a reduced number of CD4(+)CD25(+) naturally occurring regulatory T...
9.
IL-2 activation of STAT5 enhances production of IL-10 from human cytotoxic regulatory T cells, HOZOT
Tsuji-Takayama K, Suzuki M, Yamamoto M, Harashima A, Okochi A, Otani T, et al.
Exp Hematol
. 2007 Nov;
36(2):181-92.
PMID: 18023521
Objective: Interleukin (IL)-10 is an immunosuppressive cytokine produced by many cell types, including T cells. We previously reported that a novel type of regulatory T (Treg) cells, termed HOZOT, which...
10.
Yamamoto M, Tsuji-Takayama K, Suzuki M, Harashima A, Sugimoto A, Motoda R, et al.
Leuk Res
. 2007 Oct;
32(4):651-8.
PMID: 17920118
Studies of FOXP3 expression have thus far focused on T cells, including both normal and malignant T cells. In particular, adult T cell leukemia/lymphoma (ATLL) cells have been studied intensively...