Kazuaki Ichinohe
Overview
Explore the profile of Kazuaki Ichinohe including associated specialties, affiliations and a list of published articles.
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14
Citations
134
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Recent Articles
1.
Nakajima T, Wang B, Ono T, Uehara Y, Nakamura S, Ichinohe K, et al.
J Radiat Res
. 2017 Feb;
58(4):421-429.
PMID: 28201773
Molecular mechanisms of radiation dose-rate effects are not well understood. Among many possibilities, long-lasting sustained alterations in protein levels would provide critical information. To evaluate sustained effects after acute and...
2.
Hirouchi T, Akabane M, Tanaka S, Braga-Tanaka 3rd I, Todate A, Ichinohe K, et al.
Radiat Res
. 2011 Jun;
176(3):311-22.
PMID: 21692655
Radiation exposure induces acute myeloid leukemia (AML) in humans and mice. Recent studies postulated that AML stem cells of spontaneous human AML arise from hematopoietic stem cells. However, other studies...
3.
Sugihara T, Murano H, Nakamura M, Ichinohe K, Tanaka K
Radiat Res
. 2011 Mar;
175(3):328-35.
PMID: 21388276
The time course of the changes in the expression of p53-mediated genes in vivo after high doses of chronic low-dose-rate γ radiation remains unclear. Here we analyzed peripheral blood cell...
4.
Sugihara T, Murano H, Nakamura M, Ichinohe K, Tanaka K
Mol Cancer Res
. 2011 Mar;
9(4):476-84.
PMID: 21357441
The ataxia telangiectasia mutated (ATM)-p53 pathway is a well-known main signal transduction pathway for cellular responses, which is activated by γ-ray irradiation. Microarray analysis showed changes in the expressions of...
5.
Vares G, Uehara Y, Ono T, Nakajima T, Wang B, Taki K, et al.
J Radiat Res
. 2011 Feb;
52(2):249-56.
PMID: 21343681
In vivo modulation of gene expression profiles after low-dose and low-dose-rate irradiation has been observed in a variety of experimental systems. However, few studies actually investigated the underlying mechanisms for...
6.
Takai D, Todate A, Yanai T, Ichinohe K, Oghiso Y
Int J Radiat Biol
. 2011 Jan;
87(7):729-35.
PMID: 21250930
Purpose: To understand the mechanisms of life-shortening due to early neoplastic death caused by chronic low dose-rate (LDR; 20 mGy/22 h/day) radiation which accumulates to a high dose (HD; 8...
7.
Uehara Y, Ito Y, Taki K, Nenoi M, Ichinohe K, Nakamura S, et al.
Radiat Res
. 2010 Oct;
174(5):611-7.
PMID: 20954861
Changes in gene expression profiles in mouse liver induced by long-term low-dose-rate γ irradiation were examined by microarray analysis. Three groups of male C57BL/6J mice were exposed to whole-body radiation...
8.
Okudaira N, Uehara Y, Fujikawa K, Kagawa N, Ootsuyama A, Norimura T, et al.
Radiat Res
. 2010 Jan;
173(2):138-47.
PMID: 20095845
The effect of dose rate on radiation-induced mutations in two somatic tissues, the spleen and liver, was examined in transgenic gpt delta mice. These mice can be used for the...
9.
Taki K, Wang B, Nakajima T, Wu J, Ono T, Uehara Y, et al.
J Radiat Res
. 2009 Apr;
50(3):241-52.
PMID: 19398854
Measuring global gene expression using cDNA or oligonucleotide microarrays is an effective approach to understanding the complex mechanisms of the effects of radiation. However, few studies have been carried out...
10.
Tanaka K, Kohda A, Satoh K, Toyokawa T, Ichinohe K, Ohtaki M, et al.
Radiat Res
. 2009 Mar;
171(3):290-301.
PMID: 19267556
Chronological changes in the chromosome aberration rates of splenocytes from specific-pathogen-free (SPF) mice after continuous and long-term exposure to low-dose-rate gamma rays were studied. Incidences of dicentrics plus centric rings...