Kaushik Ghosal
Overview
Explore the profile of Kaushik Ghosal including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
344
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Mohammed S, Gill A, Ghosal K, Al-Dalahmeh M, Alsafadi K, Szabo S, et al.
Environ Sci Ecotechnol
. 2023 Nov;
18:100312.
PMID: 37942458
Reducing environmental pollution is a critical goal in global environmental economics and economic development. The European Union (EU) faces environmental challenges due to its development activities. Here we present a...
2.
Ghosal K, Haag M, Verghese P, West T, Veenstra T, Braunstein J, et al.
Alzheimers Dement (N Y)
. 2017 Oct;
2(2):110-120.
PMID: 29067298
Introduction: We conducted a phase Ib proof of mechanism trial to determine whether bexarotene (Targretin) increases central nervous system (CNS) apolipoprotein E (apoE) levels and alters Aβ metabolism in normal...
3.
Ghosal K, Fan Q, Dawson H, Pimplikar S
PLoS One
. 2016 Jul;
11(7):e0159435.
PMID: 27459671
Amyloid precursor protein (APP) is cleaved by gamma-secretase to simultaneously generate amyloid beta (Aβ) and APP Intracellular Domain (AICD) peptides. Aβ plays a pivotal role in Alzheimer's disease (AD) pathogenesis...
4.
Casali B, Corona A, Mariani M, Karlo J, Ghosal K, Landreth G
J Neurosci
. 2015 Jun;
35(24):9173-81.
PMID: 26085639
Alzheimer's disease (AD) is a highly prevalent disorder for which there are no effective therapies. Accumulation of amyloid β (Aβ) peptides in the brain is associated with impaired cognition and...
5.
Pitter K, Tamagno I, Feng X, Ghosal K, Amankulor N, Holland E, et al.
Glia
. 2014 Jun;
62(10):1595-607.
PMID: 24895267
In response to neurodegeneration, the adult mammalian brain activates a cellular cascade that results in reactive astrogliosis and microgliosis. The mechanism through which astrocytes become reactive and the physiological consequences...
6.
Ghosal K, Stathopoulos A, Thomas D, Phenis D, Vitek M, Pimplikar S
Neurodegener Dis
. 2012 Sep;
12(1):51-8.
PMID: 22965147
Background: Amyloid-β (Aβ) peptides derive from the amyloid precursor protein (APP) and play a pivotal role in Alzheimer's disease (AD) pathogenesis. Our previous work showed that the APP intracellular domain...
7.
Pimplikar S, Ghosal K
Stem Cell Res Ther
. 2011 Oct;
2(5):39.
PMID: 22000643
Amyloid precursor protein (APP) fascinates cell biologists because it is proteolytically processed to generate multiple peptides, including amyloid-β, which is implicated in Alzheimer's disease. However, a large body of data...
8.
APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation
Ghosal K, Stathopoulos A, Pimplikar S
PLoS One
. 2010 Aug;
5(7):e11866.
PMID: 20689579
Background: A devastating aspect of Alzheimer's disease (AD) is the progressive deterioration of memory due to neuronal loss. Amyloid precursor protein (APP) occupies a central position in AD and APP-derived...
9.
Ghosal K, Pimplikar S
Neurobiol Aging
. 2010 May;
32(12):2320.e1-9.
PMID: 20493588
The cleavage of amyloid precursor protein (APP) by presenilins simultaneously generates amyloid-β (Aβ) and APP intracellular Domain (AICD) peptides. Aβ plays a pivotal role in Alzheimer's disease (AD) pathology and...
10.
Ghosal K, Naples S, Rabe A, Killian K
Arch Insect Biochem Physiol
. 2010 Apr;
74(1):38-51.
PMID: 20422717
Immediate early genes (IEG) such as c-Fos and Fos-related antigens (FRA) have been used as markers of neuronal activation. In this study, we determined whether the expression of c-Fos/FRAs is...