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Kati Turkowski

Explore the profile of Kati Turkowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 644
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Recent Articles
1.
Abounar S, El-Nikhely N, Turkowski K, Savai R, Saeed H
Int J Mol Sci . 2024 Aug; 25(16). PMID: 39201772
Cancer cells can escape death and surveillance by the host immune system in various ways. Programmed cell death ligand 1 (PD-L1) is a transmembrane protein that is expressed by most...
2.
Arndt P, Turkowski K, Cekay M, Eul B, Grimminger F, Savai R
Clin Sci (Lond) . 2024 May; 138(11):617-634. PMID: 38785410
The tumor microenvironment (TME) plays a central role in the development of cancer. Within this complex milieu, the endothelin (ET) system plays a key role by triggering epithelial-to-mesenchymal transition, causing...
3.
Turkowski K, Herzberg F, Gunther S, Weigert A, Haselbauer T, Fink L, et al.
Oncogene . 2024 Feb; 43(16):1178-1189. PMID: 38396293
Dual-specificity phosphatase 8 (DUSP8) plays an important role as a selective c-Jun N-terminal kinase (JNK) phosphatase in mitogen-activated protein kinase (MAPK) signaling. In this study, we found that DUSP8 is...
4.
Zheng X, Sarode P, Weigert A, Turkowski K, Chelladurai P, Gunther S, et al.
Cancer Res . 2023 May; 83(14):2345-2357. PMID: 37205635
Significance: HDAC2 inhibition reverses the protumor phenotype of macrophages mediated by epigenetic modulation induced by the HDAC2-SP1 axis, indicating a therapeutic option to modify the immunosuppressive tumor microenvironment.
5.
Weigert A, Zheng X, Nenzel A, Turkowski K, Gunther S, Strack E, et al.
Nat Commun . 2022 Oct; 13(1):6078. PMID: 36241617
Fibrocytes are bone marrow-derived monocytic cells implicated in wound healing. Here, we identify their role in lung cancer progression/ metastasis. Selective manipulation of fibrocytes in mouse lung tumor models documents...
6.
Brunn D, Turkowski K, Gunther S, Weigert A, Muley T, Kriegsmann M, et al.
Cancers (Basel) . 2021 Jan; 13(2). PMID: 33430083
Transcription factors can serve as links between tumor microenvironment signaling and oncogenesis. Interferon regulatory factor 9 (IRF9) is recruited and expressed upon interferon stimulation and is dependent on cofactors that...
7.
Blank A, Kremenetskaia I, Urbantat R, Acker G, Turkowski K, Radke J, et al.
J Pathol . 2020 Oct; 253(2):160-173. PMID: 33044746
Myeloid cells are an inherent part of the microenvironment of glioblastoma multiforme (GBM). There is growing evidence for their participation in mechanisms of tumor escape, especially in the development of...
8.
Turkowski K, Herzberg F, Gunther S, Brunn D, Weigert A, Meister M, et al.
Cells . 2020 Jul; 9(8). PMID: 32707902
Investigation of the molecular dynamics in lung cancer is crucial for the development of new treatment strategies. Fibroblast growth factor (FGF) 14 belongs to the FGF family, which might play...
9.
Felsenstein M, Blank A, Bungert A, Mueller A, Ghori A, Kremenetskaia I, et al.
Cancers (Basel) . 2020 Jul; 12(7). PMID: 32668709
Glioblastoma multiforme (GBM) shows a high influx of tumor-associated macrophages (TAMs). The CCR2/CCL2 pathway is considered a relevant signal for the recruitment of TAMs and has been suggested as a...
10.
Marwitz S, Turkowski K, Nitschkowski D, Weigert A, Brandenburg J, Reiling N, et al.
Front Oncol . 2020 Feb; 9:1550. PMID: 32039023
Although immune checkpoint and targeted therapies offer remarkable benefits for lung cancer treatment, some patients do not qualify for these regimens or do not exhibit consistent benefit. Provided that lung...