Kati Juuti-Uusitalo
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Explore the profile of Kati Juuti-Uusitalo including associated specialties, affiliations and a list of published articles.
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26
Citations
379
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Recent Articles
1.
Saari J, Siddique F, Korpela S, Mantyla E, Ihalainen T, Kaukinen K, et al.
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163236
The small intestinal epithelium has an important role in nutrition, but also in drug absorption and metabolism. There are a few two-dimensional (2D) patient-derived induced pluripotent stem cell (iPSC)-based intestinal...
2.
Calejo M, Saari J, Vuorenpaa H, Vuorimaa-Laukkanen E, Kallio P, Aalto-Setala K, et al.
Acta Biomater
. 2019 Nov;
101:327-343.
PMID: 31711900
In vitro cell culture models representing the physiological and pathological features of the outer retina are urgently needed. Artificial tissue replacements for patients suffering from degenerative retinal diseases are similarly...
3.
Vuori N, Sandholm N, Kumar A, Hietala K, Syreeni A, Forsblom C, et al.
Diabetes
. 2019 Aug;
68(11):2165-2174.
PMID: 31439644
Diabetic retinopathy is a common diabetes complication that threatens the eyesight and may eventually lead to acquired visual impairment or blindness. While a substantial heritability has been reported for proliferative...
4.
Kiamehr M, Klettner A, Richert E, Koskela A, Koistinen A, Skottman H, et al.
Int J Mol Sci
. 2019 Aug;
20(15).
PMID: 31375001
In diabetic patients, high blood glucose induces alterations in retinal function and can lead to visual impairment due to diabetic retinopathy. In immortalized retinal pigment epithelial (RPE) cultures, high glucose...
5.
Ilmarinen T, Thieltges F, Hongisto H, Juuti-Uusitalo K, Koistinen A, Kaarniranta K, et al.
Acta Ophthalmol
. 2018 Dec;
97(5):e688-e699.
PMID: 30593729
Purpose: To study immunogenic properties of human embryonic stem cell-derived retinal pigment epithelium (hESC-RPE) and to evaluate subretinal xenotransplantation of hESC-RPE on porous polyethylene terephthalate (PET) in rabbits. Methods: Human...
6.
Korkka I, Viheriala T, Juuti-Uusitalo K, Uusitalo-Jarvinen H, Skottman H, Hyttinen J, et al.
Stem Cells Transl Med
. 2018 Nov;
8(2):179-193.
PMID: 30394009
Retinal pigment epithelium (RPE) performs important functions for the maintenance of photoreceptors and vision. Malfunctions within the RPE are implicated in several retinal diseases for which transplantations of stem cell-derived...
7.
Abu Khamidakh A, Rodriguez-Martinez A, Kaarniranta K, Kallioniemi A, Skottman H, Hyttinen J, et al.
Biomed Eng Online
. 2018 Aug;
17(1):102.
PMID: 30064430
Background: Wound healing of retinal pigment epithelium (RPE) is a complex process that may take place in common age-related macular degeneration eye disease. The purpose of this study was to...
8.
Juuti-Uusitalo K, Koskela A, Kivinen N, Viiri J, Hyttinen J, Reinisalo M, et al.
Int J Mol Sci
. 2017 May;
18(5).
PMID: 28534814
The impairment of autophagic and proteasomal cleansing together with changes in pigmentation has been documented in retinal pigment epithelial (RPE) cell degeneration. However, the function and co-operation of these mechanisms...
9.
Sorkio A, Haimi S, Verdoold V, Juuti-Uusitalo K, Grijpma D, Skottman H
J Tissue Eng Regen Med
. 2017 Jan;
11(11):3134-3144.
PMID: 28052579
Human embryonic stem cell-derived retinal pigment epithelial (hESC-RPE) cell therapies show tremendous potential for the treatment of retinal degenerative diseases. A tissue engineering approach, where cells are delivered to the...
10.
Abu Khamidakh A, Dos Santos F, Skottman H, Juuti-Uusitalo K, Hyttinen J
Ann Biomed Eng
. 2016 May;
44(11):3408-3420.
PMID: 27225993
Ca is a second messenger controlling vital cellular processes, including cell maturation. Changes in Ca signaling during maturation of human embryonic stem cell-derived retinal pigment epithelial cells (hESC-RPE) have not...