Kathryn Chaloner
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Explore the profile of Kathryn Chaloner including associated specialties, affiliations and a list of published articles.
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21
Citations
692
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Recent Articles
1.
Markmann J, Rickels M, Eggerman T, Bridges N, Lafontant D, Qidwai J, et al.
Am J Transplant
. 2020 Jul;
21(4):1477-1492.
PMID: 32627352
Allogeneic islet transplant offers a minimally invasive option for β cell replacement in the treatment of type 1 diabetes (T1D). The CIT consortium trial of purified human pancreatic islets (PHPI)...
2.
Hering B, Clarke W, Bridges N, Eggerman T, Alejandro R, Bellin M, et al.
Diabetes Care
. 2016 May;
39(7):1230-40.
PMID: 27208344
Objective: Impaired awareness of hypoglycemia (IAH) and severe hypoglycemic events (SHEs) cause substantial morbidity and mortality in patients with type 1 diabetes (T1D). Current therapies are effective in preventing SHEs...
3.
Zhang J, Zhang Y, Chaloner K, Stapleton J
Stat Med
. 2015 Nov;
35(8):1359-72.
PMID: 26522690
In many medical applications, combining information from multiple biomarkers could yield a better diagnosis than any single one on its own. When there is a lack of a gold standard,...
4.
Diwakar A, Adam R, Michalski A, Tamegnon M, Fischer A, Launspach J, et al.
Laryngoscope
. 2015 Apr;
125(10):2398-404.
PMID: 25827636
Objectives/hypothesis: Tracheal cartilage ring structural abnormalities have been reported in cystic fibrosis (CF) mice and pigs. Whether similar findings are present in humans with CF is unknown. We hypothesized that...
5.
Winokur P, Chaloner K, Doern G, Ferreira J, Apicella M
J Infect Dis
. 2013 May;
208(5):728-38.
PMID: 23715660
Background: Nontypeable Haemophilus influenzae (NTHi) exclusively infects humans, causing significant numbers of upper respiratory tract infections. The goal of this study was to develop a safe experimental human model of...
6.
Poole J, Foster E, Chaloner K, Hunt J, Jennings M, Bair T, et al.
J Infect Dis
. 2013 May;
208(5):720-7.
PMID: 23715658
Background: Studies of nontypeable Haemophilus influenzae (NTHi) have demonstrated that a number of genes associated with infectivity have long repeat regions associated with phase variation in expression of the respective...
7.
Zhang J, Chaloner K, McLinden J, Stapleton J
Stat Med
. 2013 Apr;
32(23):4102-17.
PMID: 23592433
Reconciling two quantitative enzyme-linked immunosorbent assay tests for an antibody to an RNA virus, in a situation without a gold standard and where false negatives may occur, is the motivation...
8.
Stapleton J, Chaloner K, Martenson J, Zhang J, Klinzman D, Xiang J, et al.
PLoS One
. 2012 Dec;
7(11):e50563.
PMID: 23209780
GBV-C infection is associated with prolonged survival and with reduced T cell activation in HIV-infected subjects not receiving combination antiretroviral therapy (cART). The relationship between GBV-C and T cell activation...
9.
Butler J, Sun X, Wertz N, Lager K, Chaloner K, Urban Jr J, et al.
Mol Immunol
. 2011 Oct;
49(3):483-94.
PMID: 22018637
Usage of variable region gene segments during development of the antibody repertoire in mammals is unresolved in part because of the complexity of the locus in mice and humans and...
10.
Zhang W, Zhang Y, Chaloner K, Stapleton J
J Stat Comput Simul
. 2011 Feb;
79(10):1245-1257.
PMID: 21304834
In medical research, it is common to have doubly censored survival data: origin time and event time are both subject to censoring. In this paper, we review simple and probability-based...