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Kathrine Thibeault

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Articles 9
Citations 55
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Recent Articles
1.
Clement A, Legare C, Desgagne V, Thibeault K, White F, Scott M, et al.
BMC Pregnancy Childbirth . 2025 Mar; 25(1):255. PMID: 40057749
Background: Gestational hypertension (GH) is linked to an increased risk of cardiometabolic diseases for both mother and child, but we lack reliable biomarkers to identify high-risk women early in pregnancy....
2.
Clement A, Legare C, Desgagne V, Thibeault K, White F, Scott M, et al.
Pregnancy Hypertens . 2024 Nov; 34:95-103. PMID: 39491415
Objectives: To identify first trimester circulating microRNAs associated with preeclampsia (PE) and assess their predictive value in two independent cohorts METHODS: Circulating microRNAs were quantified from plasma samples collected at...
3.
Legare C, Desgagne V, Thibeault K, White F, Clement A, Poirier C, et al.
Biomedicines . 2024 Jun; 12(6). PMID: 38927492
Maternal blood glucose regulation adaptation to pregnancy aims to support fetal growth but may also lead to the development of gestational diabetes mellitus, the most common pregnancy complication. MiRNAs are...
4.
Taschereau A, Thibeault K, Allard C, Juvinao-Quintero D, Perron P, Lutz S, et al.
Clin Epigenetics . 2023 Jun; 15(1):107. PMID: 37386647
Background: In utero exposure to maternal hyperglycemia has been associated with an increased risk for the development of chronic diseases in later life. These predispositions may be programmed by fetal...
5.
Legare C, Desgagne V, Thibeault K, White F, Clement A, Poirier C, et al.
Front Endocrinol (Lausanne) . 2022 Nov; 13:928508. PMID: 36440215
Aims: Our objective is to identify first-trimester plasmatic miRNAs associated with and predictive of GDM. Methods: We quantified miRNA using next-generation sequencing in discovery (Gen3G: n = 443/GDM = 56)...
6.
Thibeault K, Legare C, Desgagne V, White F, Clement A, Scott M, et al.
Biomedicines . 2022 Jul; 10(7). PMID: 35885031
Many women enter pregnancy with overweight and obesity, which are associated with complications for both the expectant mother and her child. MicroRNAs (miRNAs) are short non-coding RNAs that regulate many...
7.
Legare C, Desgagne V, Poirier C, Thibeault K, White F, Clement A, et al.
BMJ Open Diabetes Res Care . 2022 Mar; 10(2). PMID: 35246451
Introduction: Gestational diabetes mellitus (GDM) is a consequence of an imbalance between insulin sensitivity (IS) and secretion during pregnancy. MicroRNAs (miRNAs) are small and secreted RNA molecules stable in blood...
8.
Legare C, Clement A, Desgagne V, Thibeault K, White F, Guay S, et al.
Reprod Biol Endocrinol . 2022 Jan; 20(1):14. PMID: 35031065
Background: During pregnancy, maternal metabolism undergoes substantial changes to support the developing fetus. Such changes are finely regulated by different mechanisms carried out by effectors such as microRNAs (miRNAs). These...
9.
Gagne-Ouellet V, Breton E, Thibeault K, Fortin C, Desgagne V, Girard Tremblay E, et al.
Int J Mol Sci . 2020 Oct; 21(19). PMID: 33003475
The aim of this study was to identify placental DNA methylation (DNAm) variations associated with adiposity at 3 years of age. We quantified placental DNAm using the Infinium MethylationEPIC BeadChips....
10.
Gagne-Ouellet V, Breton E, Thibeault K, Fortin C, Cardenas A, Guerin R, et al.
Int J Mol Sci . 2020 Jan; 21(1). PMID: 31947745
Changes in fetal DNA methylation (DNAm) of the leptin () gene have been associated with exposure to maternal hyperglycemia, but their links with childhood obesity risk are still unclear. We...