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Andree-Anne Clement

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Articles 11
Citations 44
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Recent Articles
1.
Clement A, Legare C, Desgagne V, Thibeault K, White F, Scott M, et al.
BMC Pregnancy Childbirth . 2025 Mar; 25(1):255. PMID: 40057749
Background: Gestational hypertension (GH) is linked to an increased risk of cardiometabolic diseases for both mother and child, but we lack reliable biomarkers to identify high-risk women early in pregnancy....
2.
Clement A, Legare C, Desgagne V, Thibeault K, White F, Scott M, et al.
Pregnancy Hypertens . 2024 Nov; 34:95-103. PMID: 39491415
Objectives: To identify first trimester circulating microRNAs associated with preeclampsia (PE) and assess their predictive value in two independent cohorts METHODS: Circulating microRNAs were quantified from plasma samples collected at...
3.
Legare C, Desgagne V, Thibeault K, White F, Clement A, Poirier C, et al.
Biomedicines . 2024 Jun; 12(6). PMID: 38927492
Maternal blood glucose regulation adaptation to pregnancy aims to support fetal growth but may also lead to the development of gestational diabetes mellitus, the most common pregnancy complication. MiRNAs are...
4.
Legare C, Desgagne V, Thibeault K, White F, Clement A, Poirier C, et al.
Front Endocrinol (Lausanne) . 2022 Nov; 13:928508. PMID: 36440215
Aims: Our objective is to identify first-trimester plasmatic miRNAs associated with and predictive of GDM. Methods: We quantified miRNA using next-generation sequencing in discovery (Gen3G: n = 443/GDM = 56)...
5.
Thibeault K, Legare C, Desgagne V, White F, Clement A, Scott M, et al.
Biomedicines . 2022 Jul; 10(7). PMID: 35885031
Many women enter pregnancy with overweight and obesity, which are associated with complications for both the expectant mother and her child. MicroRNAs (miRNAs) are short non-coding RNAs that regulate many...
6.
Clement A, Lamarche D, Masse M, Legare C, Tai L, Fleury Deland L, et al.
Epigenetics . 2022 May; 17(11):1546-1561. PMID: 35603508
Neurologically deceased organ donors (NDDs) generally display an immune response involving an intense production of pro-inflammatory cytokines referred to as the cytokine storm. The sudden surge of inflammatory mediators in...
7.
Legare C, Desgagne V, Poirier C, Thibeault K, White F, Clement A, et al.
BMJ Open Diabetes Res Care . 2022 Mar; 10(2). PMID: 35246451
Introduction: Gestational diabetes mellitus (GDM) is a consequence of an imbalance between insulin sensitivity (IS) and secretion during pregnancy. MicroRNAs (miRNAs) are small and secreted RNA molecules stable in blood...
8.
Legare C, Clement A, Desgagne V, Thibeault K, White F, Guay S, et al.
Reprod Biol Endocrinol . 2022 Jan; 20(1):14. PMID: 35031065
Background: During pregnancy, maternal metabolism undergoes substantial changes to support the developing fetus. Such changes are finely regulated by different mechanisms carried out by effectors such as microRNAs (miRNAs). These...
9.
Clement A, Lacaille M, Lounis M, Biertho L, Richard D, Lemieux I, et al.
J Physiol Biochem . 2022 Jan; 78(2):527-542. PMID: 35000091
Although severe obesity is associated with insulin resistance (IR) and inflammation, secretory function of intra-abdominal adipose tissues and their relationships with IR and inflammation markers remain poorly understood. Aims were...
10.
Clement A, Desgagne V, Legare C, Guay S, Boyer M, Hutchins E, et al.
Epigenomics . 2021 May; 13(13):985-994. PMID: 33993731
To investigate the associations between high-density lipoprotein (HDL)-enriched miRNAs and the cardiometabolic profile of healthy men and women. miRNAs were quantified using next-generation sequencing of miRNAs extracted from purified HDL...