Kathrina L Marcelo
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Explore the profile of Kathrina L Marcelo including associated specialties, affiliations and a list of published articles.
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10
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438
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Recent Articles
1.
Coleman N, Marcelo K, Hopkins J, Khan N, Du R, Hong L, et al.
JCO Precis Oncol
. 2023 Jan;
7:e2200211.
PMID: 36603172
Purpose: In head and neck squamous cell carcinoma (HNSCC), mutation is a new actionable oncogene driver. We aimed to evaluate mutational variants, comutation profile, and survival outcomes of this molecularly...
2.
York B, Li F, Lin F, Marcelo K, Mao J, Dean A, et al.
Sci Rep
. 2017 Sep;
7(1):11793.
PMID: 28924233
Binding of calcium to its intracellular receptor calmodulin (CaM) activates a family of Ca/CaM-dependent protein kinases. CaMKK2 (Ca/CaM-dependent protein kinase kinase 2) is a central member of this kinase family...
3.
Marcelo K, Means A, York B
Trends Endocrinol Metab
. 2016 Jul;
27(10):706-718.
PMID: 27449752
Calcium (Ca(2+)) is an essential ligand that binds its primary intracellular receptor calmodulin (CaM) to trigger a variety of downstream processes and pathways. Central to the actions of Ca(2+)/CaM is...
4.
Fleet T, Stashi E, Zhu B, Rajapakshe K, Marcelo K, Kettner N, et al.
J Biol Rhythms
. 2016 Jul;
31(5):443-60.
PMID: 27432117
Circadian rhythmicity is a fundamental process that synchronizes behavioral cues with metabolic homeostasis. Disruption of daily cycles due to jet lag or shift work results in severe physiological consequences including...
5.
Fang J, Gritz E, Marcelo K, Hirschi K
J Vis Exp
. 2016 Jun;
(112).
PMID: 27341393
The specification of hemogenic endothelial cells from embryonic vascular endothelium occurs during brief developmental periods within distinct tissues, and is necessary for the emergence of definitive HSPC from the murine...
6.
Marcelo K, Ribar T, Means C, Tsimelzon A, Stevens R, Ilkayeva O, et al.
Mol Endocrinol
. 2016 Mar;
30(5):557-72.
PMID: 27003444
A number of epidemiological studies have implicated calcium (Ca(2+)) signaling as a major factor in obesity that contributes to aberrant systems metabolism. Somewhat paradoxically, obesity correlates with decreased circulating Ca(2+)...
7.
Marcelo K, Lin F, Rajapakshe K, Dean A, Gonzales N, Coarfa C, et al.
J Biol Methods
. 2015 Oct;
2(3).
PMID: 26504887
Each cell type responds uniquely to stress and fractionally contributes to global and tissue-specific stress responses. Hepatocytes, liver macrophages (MΦ), and sinusoidal endothelial cells (SEC) play functionally important and interdependent...
8.
Lin F, Marcelo K, Rajapakshe K, Coarfa C, Dean A, Wilganowski N, et al.
Hepatology
. 2015 Apr;
62(2):505-20.
PMID: 25847065
Unlabelled: Hepatic cancer is one of the most lethal cancers worldwide. Here, we report that the expression of Ca(2+) /calmodulin-dependent protein kinase kinase 2 (CaMKK2) is significantly up-regulated in hepatocellular...
9.
Marcelo K, Sills T, Coskun S, Vasavada H, Sanglikar S, Goldie L, et al.
Dev Cell
. 2013 Dec;
27(5):504-15.
PMID: 24331925
Delineating the mechanism or mechanisms that regulate the specification of hemogenic endothelial cells from primordial endothelium is critical for optimizing their derivation from human stem cells for clinical therapies. We...
10.
Marcelo K, Goldie L, Hirschi K
Circ Res
. 2013 Apr;
112(9):1272-87.
PMID: 23620236
The circulatory system is the first organ system to develop in the vertebrate embryo and is critical throughout gestation for the delivery of oxygen and nutrients to, as well as...