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Kathrin Jantsch

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Articles 9
Citations 89
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Recent Articles
1.
Belleza O, Saridakis I, Singer N, Westergaard X, Armentia Matheu S, Lemmerer M, et al.
Chem Sci . 2025 Mar; PMID: 40070471
Fluorescent labeling techniques have enabled the visualization of various biomolecules, cellular structures, and their associated physiological processes. At the same time, there remains a demand for developing novel fluorescent compounds...
2.
Alberto-Silva A, Hemmer S, Bock H, da Silva L, Scott K, Kastner N, et al.
J Neurochem . 2024 Jun; 168(9):2022-2042. PMID: 38898705
3,4-Methylenedioxymethamphetamine (MDMA, 'ecstasy') is re-emerging in clinical settings as a candidate for the treatment of specific neuropsychiatric disorders (e.g. post-traumatic stress disorder) in combination with psychotherapy. MDMA is a psychoactive...
3.
Alberto-Silva A, Hemmer S, Bock H, da Silva L, Scott K, Kastner N, et al.
bioRxiv . 2024 Apr; PMID: 38645142
3,4-Methylenedioxymethamphetamine (MDMA, ' ) is re-emerging in clinical settings as a candidate for the treatment of specific psychiatric disorders (e.g. post-traumatic stress disorder) in combination with psychotherapy. MDMA is a...
4.
Niello M, Sideromenos S, Gradisch R, O Shea R, Schwazer J, Maier J, et al.
Proc Natl Acad Sci U S A . 2023 Feb; 120(6):e2114204120. PMID: 36730201
Psychostimulants interacting with the dopamine transporter (DAT) can be used illicitly or for the treatment of specific neuropsychiatric disorders. However, they can also produce severe and persistent adverse events. Often,...
5.
Khanppnavar B, Maier J, Herborg F, Gradisch R, Lazzarin E, Luethi D, et al.
Nat Commun . 2022 Nov; 13(1):6714. PMID: 36344565
Organic cation transporters (OCTs) facilitate the translocation of catecholamines, drugs and xenobiotics across the plasma membrane in various tissues throughout the human body. OCT3 plays a key role in low-affinity,...
6.
Nadal-Gratacos N, Alberto-Silva A, Rodriguez-Soler M, Urquizu E, Espinosa-Velasco M, Jantsch K, et al.
Front Pharmacol . 2021 Nov; 12:749429. PMID: 34764870
Several new synthetic cathinones, which mimic the effect of classical psychostimulants such as cocaine or MDMA, have appeared in the global illicit drug market in the last decades. In fact,...
7.
Niello M, Cintulova D, Raithmayr P, Holy M, Jantsch K, Colas C, et al.
Front Pharmacol . 2021 Apr; 12:654061. PMID: 33897439
Mephedrone is a largely abused psychostimulant. It elicits the release of monoamines via the high affinity transporters for dopamine (DAT), norepinephrine (NET) and serotonin (SERT). Stereoselective metabolic reactions are involved...
8.
Niello M, Cintulova D, Hellsberg E, Jantsch K, Holy M, Ayatollahi L, et al.
Neuropharmacology . 2019 Apr; 161:107615. PMID: 31028773
The transporters for dopamine (DAT) and serotonin (SERT) are important targets in the treatment of psychiatric disorders including major depression, anxiety and attention-deficit hyperactivity disorder. Drugs acting at these transporters...
9.
Yang J, Larson G, Konrad L, Shetty M, Holy M, Jantsch K, et al.
J Biol Chem . 2018 Dec; 294(10):3419-3431. PMID: 30587577
Several protein kinases, including protein kinase C, Ca/calmodulin-dependent protein kinase II, and extracellular signal-regulated kinase, play key roles in the regulation of dopamine transporter (DAT) functions. These functions include surface...
10.
Maier J, Mayer F, Luethi D, Holy M, Jantsch K, Reither H, et al.
Neuropharmacology . 2018 Jun; 138:282-291. PMID: 29908239
(±)-cis-4,4'-Dimethylaminorex (4,4'-DMAR) is a new psychoactive substance (NPS) that has been associated with 31 fatalities and other adverse events in Europe between June 2013 and February 2014. We used in ...