Kathrin Cordts
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Explore the profile of Kathrin Cordts including associated specialties, affiliations and a list of published articles.
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19
Citations
172
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Recent Articles
1.
Schwedhelm E, Cordts K, Moritz E, Wesemann R, Choe C, Boger R, et al.
J Appl Lab Med
. 2022 Sep;
7(6):1272-1282.
PMID: 36172979
Background: Low levels of the endogenous amino acid L-homoarginine are a risk factor for cardiovascular morbidity and mortality. For individual risk prediction, commercially available test systems are mandatory. This study...
2.
Hannemann J, Cordts K, Seniuk A, Choe C, Schmidt-Hutten L, Duque Escobar J, et al.
Front Physiol
. 2021 Sep;
12:703069.
PMID: 34483959
Chronic hypoxia induces pulmonary and cardiovascular pathologies, including pulmonary hypertension (PH). L-arginine:glycine amidinotransferase (AGAT) is essential for homoarginine (hArg) and guanidinoacetate synthesis, the latter being converted to creatine by guanidinoacetate...
3.
Sasani A, Hornig S, Grzybowski R, Cordts K, Hanff E, Tsikas D, et al.
Amino Acids
. 2019 Dec;
52(1):73-85.
PMID: 31853708
Statin-induced myopathy affects more than 10 million people worldwide. But discontinuation of statin treatment increases mortality and cardiovascular events. Recently, L-arginine:glycine amidinotransferase (AGAT) gene was associated with statin-induced myopathy in...
4.
Choe C, Lezius S, Cordts K, Gerloff C, Boger R, Schwedhelm E, et al.
Neurol Sci
. 2019 Sep;
41(1):149-153.
PMID: 31482247
Background: Guanidino compounds, including asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA), and L-homoarginine (hArg), have been associated with cardio- and cerebrovascular events and risk. We aimed to study if low hArg/ADMA...
5.
Cordts K, Seelig D, Lund N, Carrier L, Boger R, Avanesov M, et al.
Biomolecules
. 2019 Jul;
9(7).
PMID: 31337005
Despite genetic heterogeneity, early manifestation of diastolic dysfunction (DD) is common in hypertrophic cardiomyopathy (HCM). Nitric oxide (NO) may contribute to myocardial relaxation. NO synthases (NOS) use l-arginine (Arg) as...
6.
Bollenbach A, Cordts K, Hanff E, Atzler D, Choe C, Schwedhelm E, et al.
Anal Biochem
. 2019 Apr;
577:59-66.
PMID: 31028716
l-Homoarginine (hArg) is biosynthesized from l-arginine (Arg) and l-lysine (Lys) by arginine:glycine amidinotransferase (AGAT). AGAT also catalyzes the formation of guanidinoacetate (GAA) from Arg and glycine (Gly). GAA is converted...
7.
Cordts K, Grzybowski R, Lezius S, Luneburg N, Atzler D, Neu A, et al.
J Neurol Sci
. 2019 Jan;
397:156-161.
PMID: 30640152
Introduction: Guanidino compounds, including l-homoarginine (l-hArg), symmetric dimethylarginine (SDMA), asymmetric dimethylarginine (ADMA) and l-arginine (l-Arg) are associated with mortality, fatal strokes, stroke incidence, and atherosclerosis. Objectives: We aimed to study...
8.
Loso J, Lund N, Avanesov M, Muschol N, Lezius S, Cordts K, et al.
Front Cardiovasc Med
. 2018 Aug;
5:108.
PMID: 30159316
Fabry disease (FD) is characterized by early development of vasculopathy and endothelial dysfunction. However, it is unclear whether these findings also play a pivotal role in cardiac manifestation. As Fabry...
9.
Baldassarri F, Schwedhelm E, Atzler D, Boger R, Cordts K, Haller B, et al.
Biomarkers
. 2018 Apr;
23(6):540-550.
PMID: 29619838
Objective: Elevated levels of arginine derivatives in the NO pathway, such as asymmetric dimethylarginine (ADMA), are related to disease severity and reduced exercise capacity in heart failure (HF). We investigated...
10.
Schonhoff M, Weineck G, Hoppe J, Hornig S, Cordts K, Atzler D, et al.
J Clin Neurosci
. 2018 Feb;
50:237-241.
PMID: 29396070
l-homoarginine (l-hArg) is an endogenous non-proteinogenic amino acid. Low l-hArg concentrations are associated with increased all-cause mortality, fatal strokes, and worse outcome after stroke. On the other hand, oral supplementation...