Kathleen E Stirrups
Overview
Explore the profile of Kathleen E Stirrups including associated specialties, affiliations and a list of published articles.
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29
Citations
3517
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Recent Articles
1.
Cooper D, Lear S, Watson L, Shaw A, Ferris M, Doffinger R, et al.
J Infect
. 2022 Sep;
85(5):557-564.
PMID: 36058413
Objectives: To describe the risk factors for SARS-CoV-2 infection in UK healthcare workers (HCWs). Methods: We conducted a prospective sero-epidemiological study of HCWs at a major UK teaching hospital using...
2.
Wang J, Kotagiri P, Lyons P, Al-Lamki R, Mescia F, Bergamaschi L, et al.
iScience
. 2022 Feb;
25(3):103971.
PMID: 35224470
Clotting Factor V (FV) is primarily synthesized in the liver and when cleaved by thrombin forms pro-coagulant Factor Va (FVa). Using whole blood RNAseq and scRNAseq of peripheral blood mononuclear...
3.
Downes K, Zhao X, Gleadall N, McKinney H, Kempster C, Batista J, et al.
Blood Adv
. 2021 Sep;
6(7):2319-2330.
PMID: 34581777
The interindividual variation in the functional response of platelets to activation by agonists is heritable. Genome-wide association studies (GWASs) of quantitative measures of platelet function have identified fewer than 20...
4.
Gleadall N, Veldhuisen B, Gollub J, Butterworth A, Ord J, Penkett C, et al.
Blood Adv
. 2020 Aug;
4(15):3495-3506.
PMID: 32750130
Each year, blood transfusions save millions of lives. However, under current blood-matching practices, sensitization to non-self-antigens is an unavoidable adverse side effect of transfusion. We describe a universal donor typing...
5.
Thaventhiran J, Lango Allen H, Burren O, Rae W, Greene D, Staples E, et al.
Nature
. 2020 Jul;
584(7819):E2.
PMID: 32678341
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
6.
Turro E, Astle W, Megy K, Graf S, Greene D, Shamardina O, et al.
Nature
. 2020 Jun;
583(7814):96-102.
PMID: 32581362
Most patients with rare diseases do not receive a molecular diagnosis and the aetiological variants and causative genes for more than half such disorders remain to be discovered. Here we...
7.
Thaventhiran J, Lango Allen H, Burren O, Rae W, Greene D, Staples E, et al.
Nature
. 2020 Jun;
583(7814):90-95.
PMID: 32499645
Primary immunodeficiency (PID) is characterized by recurrent and often life-threatening infections, autoimmunity and cancer, and it poses major diagnostic and therapeutic challenges. Although the most severe forms of PID are...
8.
Levine A, Chan M, Sadeghi-Alavijeh O, Wong E, Cook H, Ashford S, et al.
J Am Soc Nephrol
. 2020 Jan;
31(2):365-373.
PMID: 31919107
Background: Primary membranoproliferative GN, including complement 3 (C3) glomerulopathy, is a rare, untreatable kidney disease characterized by glomerular complement deposition. Complement gene mutations can cause familial C3 glomerulopathy, and studies...
9.
Bury L, Megy K, Stephens J, Grassi L, Greene D, Gleadall N, et al.
Hum Mutat
. 2019 Sep;
41(1):277-290.
PMID: 31562665
The heterogeneous manifestations of MYH9-related disorder (MYH9-RD), characterized by macrothrombocytopenia, Döhle-like inclusion bodies in leukocytes, bleeding of variable severity with, in some cases, ear, eye, kidney, and liver involvement, make...
10.
Lentaigne C, Greene D, Sivapalaratnam S, Favier R, Seyres D, Thys C, et al.
Blood
. 2019 Jun;
134(23):2070-2081.
PMID: 31217188
To identify novel causes of hereditary thrombocytopenia, we performed a genetic association analysis of whole-genome sequencing data from 13 037 individuals enrolled in the National Institute for Health Research (NIHR)...