Katherine J L Jackson
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Explore the profile of Katherine J L Jackson including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
2019
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Recent Articles
1.
Young C, Singh M, Jackson K, Field M, Peters T, Angioletti-Uberti S, et al.
Immunity
. 2025 Jan;
58(2):412-430.e10.
PMID: 39818208
The unexplained association between infection and autoimmune disease is strongest for hepatitis C virus-induced cryoglobulinemic vasculitis (HCV-cryovas). To analyze its origins, we traced the evolution of pathogenic rheumatoid factor (RF)...
2.
Phetsouphanh C, Jacka B, Ballouz S, Jackson K, Wilson D, Manandhar B, et al.
Nat Commun
. 2024 Apr;
15(1):3315.
PMID: 38632311
This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC) compared to age and gender matched...
3.
Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection
Cooper L, Xu H, Polmear J, Kealy L, Szeto C, Pang E, et al.
Immunity
. 2024 Apr;
57(5):1037-1055.e6.
PMID: 38593796
Memory B cells (MBCs) are key providers of long-lived immunity against infectious disease, yet in chronic viral infection, they do not produce effective protection. How chronic viral infection disrupts MBC...
4.
Mina E, Jackson K, Crawford A, Faulks M, Pathmanandavel K, Acquarola N, et al.
J Clin Immunol
. 2024 Feb;
44(3):66.
PMID: 38363477
B cells and their secreted antibodies are fundamental for host-defense against pathogens. The generation of high-affinity class switched antibodies results from both somatic hypermutation (SHM) of the immunoglobulin (Ig) variable...
5.
Rodriguez O, Safonova Y, Silver C, Shields K, Gibson W, Kos J, et al.
Nat Commun
. 2023 Jul;
14(1):4419.
PMID: 37479682
Variation in the antibody response has been linked to differential outcomes in disease, and suboptimal vaccine and therapeutic responsiveness, the determinants of which have not been fully elucidated. Countering models...
6.
Masle-Farquhar E, Jackson K, Peters T, Al-Eryani G, Singh M, Payne K, et al.
Immunity
. 2022 Nov;
55(12):2386-2404.e8.
PMID: 36446385
The association between cancer and autoimmune disease is unexplained, exemplified by T cell large granular lymphocytic leukemia (T-LGL) where gain-of-function (GOF) somatic STAT3 mutations correlate with co-existing autoimmunity. To investigate...
7.
Yang R, Avery D, Jackson K, Ogishi M, Benhsaien I, Du L, et al.
Sci Immunol
. 2022 Jul;
7(73):eabq3277.
PMID: 35867801
High-level expression of the transcription factor T-bet characterizes a phenotypically distinct murine B cell population known as "age-associated B cells" (ABCs). T-bet-deficient mice have reduced ABCs and impaired humoral immunity....
8.
Langley D, Schofield P, Nevoltris D, Jackson J, Jackson K, Peters T, et al.
Proc Natl Acad Sci U S A
. 2022 Jul;
119(28):e2123212119.
PMID: 35867757
Humans lack the capacity to produce the Galα1-3Galβ1-4GlcNAc (α-gal) glycan, and produce anti-α-gal antibodies upon exposure to the carbohydrate on a diverse set of immunogens, including commensal gut bacteria, malaria...
9.
Jackson K, Kos J, Lees W, Gibson W, Smith M, Peres A, et al.
Front Immunol
. 2022 Jun;
13:888555.
PMID: 35720344
The immunoglobulin genes of inbred mouse strains that are commonly used in models of antibody-mediated human diseases are poorly characterized. This compromises data analysis. To infer the immunoglobulin genes of...
10.
Burnett D, Jackson K, Langley D, Aggrawal A, Stella A, Johansen M, et al.
Immunity
. 2021 Nov;
54(12):2908-2921.e6.
PMID: 34788600
Viral mutations are an emerging concern in reducing SARS-CoV-2 vaccination efficacy. Second-generation vaccines will need to elicit neutralizing antibodies against sites that are evolutionarily conserved across the sarbecovirus subgenus. Here,...