Katherine E Gadek
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Explore the profile of Katherine E Gadek including associated specialties, affiliations and a list of published articles.
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5
Citations
41
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Recent Articles
1.
Searcy M, Larsen 4th R, Stevens B, Zhang Y, Jin H, Drummond C, et al.
Nat Commun
. 2023 Nov;
14(1):7291.
PMID: 37968277
Fusion-positive rhabdomyosarcoma (FP-RMS) driven by the expression of the PAX3-FOXO1 (P3F) fusion oncoprotein is an aggressive subtype of pediatric rhabdomyosarcoma. FP-RMS histologically resembles developing muscle yet occurs throughout the body...
2.
Langdon C, Gadek K, Garcia M, Evans M, Reed K, Bush M, et al.
Nat Commun
. 2021 Sep;
12(1):5520.
PMID: 34535684
PTEN promoter hypermethylation is nearly universal and PTEN copy number loss occurs in ~25% of fusion-negative rhabdomyosarcoma (FN-RMS). Here we show Pten deletion in a mouse model of FN-RMS results...
3.
Gadek K, Wang H, Hall M, Sungello M, Libby A, Maclaskey D, et al.
PLoS One
. 2018 Jan;
13(1):e0190963.
PMID: 29304082
Excessive circulating triglycerides due to reduction or loss of lipoprotein lipase activity contribute to hypertriglyceridemia and increased risk for pancreatitis. The only gene therapy treatment for lipoprotein lipase deficiency decreases...
4.
Isolation, Culture, Functional Assays, and Immunofluorescence of Myofiber-Associated Satellite Cells
Vogler T, Gadek K, Cadwallader A, Elston T, Olwin B
Methods Mol Biol
. 2016 Aug;
1460:141-62.
PMID: 27492171
Adult skeletal muscle stem cells, termed satellite cells, regenerate and repair the functional contractile cells in adult skeletal muscle called myofibers. Satellite cells reside in a niche between the basal...
5.
Starr T, Gadek K, Yoder J, Flatz R, Smith C
Mol Ecol
. 2012 Nov;
22(2):437-49.
PMID: 23190404
The angiosperms are by far the largest group of terrestrial plants. Their spectacular diversity is often attributed to specialized pollination. Obligate pollination mutualisms where both a plant and its pollinator...