Katharina Horn
Overview
Explore the profile of Katharina Horn including associated specialties, affiliations and a list of published articles.
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13
Citations
655
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Recent Articles
1.
Langhammer M, Schopf J, Jaquet T, Horn K, Angel M, Spohr C, et al.
Leukemia
. 2023 May;
37(7):1474-1484.
PMID: 37161070
The persistence of leukemic stem cells (LSCs) represents a problem in the therapy of chronic myeloid leukemia (CML). Hence, it is of utmost importance to explore the underlying mechanisms to...
2.
Capellmann S, Sonntag R, Schuler H, Meurer S, Gan L, Kauffmann M, et al.
Front Immunol
. 2023 Apr;
14:1154416.
PMID: 37063827
Mast cells (MCs) are immune cells of the myeloid lineage distributed in tissues throughout the body. Phenotypically, they are a heterogeneous group characterized by different protease repertoires stored in secretory...
3.
Chen Z, Singh P, Horn K, Calvano M, Kaneki S, McCrae K, et al.
Blood Adv
. 2022 Nov;
7(7):1156-1167.
PMID: 36409609
A dysregulated plasma contact system is involved in various pathological conditions, such as hereditary angioedema, Alzheimer disease, and sepsis. We previously showed that the 3E8 anti-high molecular weight kininogen (anti-HK)...
4.
Singh P, Chen Z, Horn K, Norris E
Res Pract Thromb Haemost
. 2022 Oct;
6(7):e12815.
PMID: 36254255
Background: The contact system is initiated by factor (F) XII activation and the assembly of high molecular weight kininogen (HK) with either FXI or prekallikrein (PK) on a negatively charged...
5.
Chen Z, Kumar Singh P, Horn K, Strickland S, Norris E
Blood Adv
. 2022 Feb;
6(10):3090-3101.
PMID: 35147669
Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia. Vascular abnormalities and neuroinflammation play roles in AD pathogenesis. Plasma contact activation, which leads to fibrin clot...
6.
Chen Z, Singh P, Wong J, Horn K, Strickland S, Norris E
Proc Natl Acad Sci U S A
. 2019 Oct;
116(46):22921-22923.
PMID: 31659032
Bradykinin is a proinflammatory factor that mediates angioedema and inflammation in many diseases. It is a key player in some types of hereditary angioedema and is involved in septic shock,...
7.
Oelkrug C, Horn K, Makert G, Schubert A
Anticancer Res
. 2015 Apr;
35(4):2085-91.
PMID: 25862864
The electrical current exclusion (ECE) principle provides an alternative to common methods of cell diameter measurement and especially in atrophy and cancer associated cachexia research. C2C12 myoblasts were differentiated into...
8.
Static and dynamic components synergize to form a stable survival niche for bone marrow plasma cells
Zehentmeier S, Roth K, Cseresnyes Z, Sercan O, Horn K, Niesner R, et al.
Eur J Immunol
. 2014 Apr;
44(8):2306-17.
PMID: 24777940
In the bone marrow (BM), memory plasma cells (PCs) survive for long time periods in dedicated microenvironmental survival niches, resting in terms of proliferation. Several cell types, such as eosinophils...
9.
Shen P, Roch T, Lampropoulou V, OConnor R, Stervbo U, Hilgenberg E, et al.
Nature
. 2014 Feb;
507(7492):366-370.
PMID: 24572363
B lymphocytes have critical roles as positive and negative regulators of immunity. Their inhibitory function has been associated primarily with interleukin 10 (IL-10) because B-cell-derived IL-10 can protect against autoimmune...
10.
Shebzukhov Y, Horn K, Brazhnik K, Drutskaya M, Kuchmiy A, Kuprash D, et al.
Eur J Immunol
. 2013 Sep;
44(1):251-64.
PMID: 24009130
Tumor necrosis factor (TNF) is one of the key primary response genes in the immune system that can be activated by a variety of stimuli. Previous analysis of chromatin accessibility...