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Katelyn A Doxtader

Explore the profile of Katelyn A Doxtader including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Zhang C, Tunes L, Hsieh M, Wang P, Kumar A, Khadgi B, et al.
bioRxiv . 2023 Mar; PMID: 36993753
Chemical modification of RNAs is important for post-transcriptional gene regulation. The METTL3-METTL14 complex generates most -methyladenosine (m A) modifications in mRNAs, and dysregulated methyltransferase expression has been linked to numerous...
2.
Doxtader K, Nam Y
Mol Cell . 2019 Aug; 75(3):417-418. PMID: 31398320
In two recent publications in Molecular Cell,Boulias et al. (2019) and Sendinc et al. (2019) use complementary approaches to map mAm modification sites transcriptome-wide and demonstrate that mAm can repress...
3.
Doxtader K, Wang P, Scarborough A, Seo D, Conrad N, Nam Y
Mol Cell . 2018 Sep; 71(6):1001-1011.e4. PMID: 30197297
S-adenosylmethionine (SAM) is an essential metabolite that acts as a cofactor for most methylation events in the cell. The N-methyladenosine (mA) methyltransferase METTL16 controls SAM homeostasis by regulating the abundance...
4.
Johnson M, Ghalei H, Doxtader K, Karbstein K, Stroupe M
Structure . 2017 Jan; 25(2):329-340. PMID: 28111018
Late-stage 40S ribosome assembly is a highly regulated dynamic process that occurs in the cytoplasm, alongside the full translation machinery. Seven assembly factors (AFs) regulate and facilitate maturation, but the...
5.
Wang P, Doxtader K, Nam Y
Mol Cell . 2016 Jul; 63(2):306-317. PMID: 27373337
N(6)-methyladenosine (m(6)A) is a prevalent, reversible chemical modification of functional RNAs and is important for central events in biology. The core m(6)A writers are Mettl3 and Mettl14, which both contain...