Katarzyna Szczepanska
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Explore the profile of Katarzyna Szczepanska including associated specialties, affiliations and a list of published articles.
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57
Citations
265
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Recent Articles
1.
Degutis M, Lazewska D, Barut J, Bialon M, Latacz G, Szczepanska K, et al.
Biomed Pharmacother
. 2025 Jan;
183:117850.
PMID: 39818100
Neuropathic pain is a disorder affecting the somatosensory nervous system. However, this condition is also characterized by significant neuroinflammation, primarily involving CNS-resident non-neuronal cells. A promising target for developing new...
2.
Karcz T, Szczepanska K, Mogilski S, Moroz A, Olejarz-Maciej A, Humphrys L, et al.
ACS Chem Neurosci
. 2024 Dec;
15(24):4441-4457.
PMID: 39652796
In this study, we selected 12 guanidine derivatives from the previously described ligand library and determined their affinity at histamine H and H receptors (HR and HR, respectively). Moreover, we...
3.
Filimonow K, Szczepanska K, Meglicki M, Wolinska-Niziol L, Suwinska A, Maleszewski M
Theriogenology
. 2024 Dec;
234():1-8.
PMID: 39626542
In this work, we aimed to investigate whether Pecam-1 (platelet endothelial cell adhesion molecule 1) surface protein of ICM cells is involved in primitive endoderm (PrE) differentiation. For this purpose,...
4.
Winek E, Wolinska-Niziol L, Szczepanska K, Szpakowska A, Gewartowska O, Wysocka I, et al.
Biol Reprod
. 2024 Nov;
112(1):31-45.
PMID: 39504567
In this work, we aimed to determine the role of activin A during crucial events of mouse embryogenesis and distinguish the function of the protein of zygotic origin and the...
5.
Stasiak A, Honkisz-Orzechowska E, Gajda Z, Wagner W, Popiolek-Barczyk K, Kuder K, et al.
Int J Mol Sci
. 2024 Aug;
25(15).
PMID: 39125607
The future of therapy for neurodegenerative diseases (NDs) relies on new strategies targeting multiple pharmacological pathways. Our research led to obtaining the compound AR71 [(E)-3-(3,4,5-trimethoxyphenyl)-1-(4-(3-(piperidin-1-yl)propoxy)phenyl)prop-2-en-1-one], which has high affinity for...
6.
Kotanska M, Zadrozna M, Kubacka M, Mika K, Szczepanska K, Nowak B, et al.
Pharmaceuticals (Basel)
. 2024 Jul;
17(7).
PMID: 39065709
Background: Numerous studies highlight the critical role that neural histamine plays in feeding behavior, which is controlled by central histamine H and H receptors. This is the fundamental motivation for...
7.
Michalska B, Dziegielewski M, Godyn J, Werner T, Bajda M, Karcz T, et al.
ACS Chem Neurosci
. 2024 Mar;
15(6):1206-1218.
PMID: 38440987
This study examines the properties of a novel series of 4-oxypiperidines designed and synthesized as histamine HR antagonists/inverse agonists based on the structural modification of two lead compounds, viz., and...
8.
Nawrot N, Wojciechowska E, Mohsin M, Kuittinen S, Pappinen A, Matej-Lukowicz K, et al.
Sci Rep
. 2023 Dec;
13(1):22417.
PMID: 38104172
Floating treatment wetlands (FTWs) are a sustainable solution to treat polluted water, but their role in chromium (Cr(III)) removal under neutral pH conditions remains poorly understood. This study evaluated the...
9.
Mogilski S, Kubacka M, Swierczek A, Wyska E, Szczepanska K, Sapa J, et al.
Pharmaceuticals (Basel)
. 2023 Oct;
16(10).
PMID: 37895952
Itch and pain are closely related but distinct sensations that share largely overlapping mediators and receptors. We hypothesized that the novel, multi-target compound E153 has the potential to attenuate pain...
10.
Szczepanska K, Bojarski A, Popik P, Malikowska-Racia N
Pharmacol Rep
. 2023 Aug;
75(5):1291-1298.
PMID: 37572216
Background: Although the terms "agonist" and "antagonist" have been used to classify sigma-1 receptor (σR) ligands, an unambiguous definition of the functional activity is often hard. In order to determine...