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Kasturi Chakraborty

Explore the profile of Kasturi Chakraborty including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 566
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Recent Articles
1.
Gao J, Liu R, Huang K, Li Z, Sheng X, Chakraborty K, et al.
Proc Natl Acad Sci U S A . 2025 Mar; 122(10):e2404899122. PMID: 40030031
The recently identified histone modification lysine lactylation can be stimulated by L-lactate and glycolysis. Although the chemical group added upon lysine lactylation was originally proposed to be the L-enantiomer of...
2.
Cui C, Chakraborty K, Tang X, Schoenfelt K, Hoffman A, Blank A, et al.
Nat Nanotechnol . 2021 Nov; 16(12):1394-1402. PMID: 34764452
Activating CD8 T cells by antigen cross-presentation is remarkably effective at eliminating tumours. Although this function is traditionally attributed to dendritic cells, tumour-associated macrophages (TAMs) can also cross-present antigens. TAMs...
3.
Suresh B, Saminathan A, Chakraborty K, Zajac M, Cui C, Becker L, et al.
Proc Natl Acad Sci U S A . 2021 Oct; 118(41). PMID: 34607961
Lysosomes adopt dynamic, tubular states that regulate antigen presentation, phagosome resolution, and autophagy. Tubular lysosomes are studied either by inducing autophagy or by activating immune cells, both of which lead...
4.
Chakraborty K, Anees P, Surana S, Martin S, Aburas J, Moutel S, et al.
Elife . 2021 Jul; 10. PMID: 34318748
Nucleic acid nanodevices present great potential as agents for logic-based therapeutic intervention as well as in basic biology. Often, however, the disease targets that need corrective action are localized in...
5.
Cui C, Chakraborty K, Tang X, Zhou G, Schoenfelt K, Becker K, et al.
Cell . 2021 May; 184(12):3163-3177.e21. PMID: 33964209
Cancer cell genetic variability and similarity to host cells have stymied development of broad anti-cancer therapeutics. Our innate immune system evolved to clear genetically diverse pathogens and limit host toxicity;...
6.
Zajac M, Chakraborty K, Saha S, Mahadevan V, Infield D, Accardi A, et al.
J Cell Sci . 2020 Jan; 133(2). PMID: 31974277
Impaired chloride transport affects diverse processes ranging from neuron excitability to water secretion, which underlie epilepsy and cystic fibrosis, respectively. The ability to image chloride fluxes with fluorescent probes has...
7.
Dan K, Veetil A, Chakraborty K, Krishnan Y
Nat Nanotechnol . 2019 Feb; 14(3):252-259. PMID: 30742135
Cellular reporters of enzyme activity are based on either fluorescent proteins or small molecules. Such reporters provide information corresponding to wherever inside cells the enzyme is maximally active and preclude...
8.
Narayanaswamy N, Chakraborty K, Saminathan A, Zeichner E, Leung K, Devany J, et al.
Nat Methods . 2019 Jan; 16(2):205. PMID: 30643216
The originally published paper has been updated to include the following new reference, added as ref. 18: Albrecht, T., Zhao, Y., Nguyen, T. H., Campbell, R. E. & Johnson, J....
9.
Narayanaswamy N, Chakraborty K, Saminathan A, Zeichner E, Leung K, Devany J, et al.
Nat Methods . 2018 Dec; 16(1):95-102. PMID: 30532082
It is extremely challenging to quantitate lumenal Ca in acidic Ca stores of the cell because all Ca indicators are pH sensitive, and Ca transport is coupled to pH in...
10.
Leung K, Chakraborty K, Saminathan A, Krishnan Y
Nat Nanotechnol . 2018 Dec; 14(2):176-183. PMID: 30510277
Lysosomes are multifunctional, subcellular organelles with roles in plasma membrane repair, autophagy, pathogen degradation and nutrient sensing. Dysfunctional lysosomes underlie Alzheimer's disease, Parkinson's disease and rare lysosomal storage diseases, but...