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Kasper Holst Hansen

Explore the profile of Kasper Holst Hansen including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Byeon C, Kinney T, Saricayir H, Hansen K, Scott F, Scott F, et al.
Angew Chem Int Ed Engl . 2025 Jan; e202418146. PMID: 39777964
Bacterial biofilms are major contributors to persistent infections and antimicrobial resistance, posing significant challenges to treatment. However, obtaining high-resolution structural information on native bacterial biofilms has remained elusive due to...
2.
Byeon C, Kinney T, Saricayir H, Hansen K, Scott F, Srinivasa S, et al.
bioRxiv . 2024 Oct; PMID: 39386544
Bacterial biofilms cause persistent infections that are difficult to treat and contribute greatly to antimicrobial resistance. However, high-resolution structural information on native bacterial biofilms remain very limited. This limitation is...
3.
Byeon C, Hansen K, DePas W, Akbey U
Solid State Nucl Magn Reson . 2024 Sep; 134:101970. PMID: 39312837
We present a high-resolution magic-angle spinning (MAS) solid-state NMR (ssNMR) study to characterize nontuberculous mycobacteria (NTM). We studied two different NTM strains, Mycobacterium smegmatis, a model, non-pathogenic strain, and Mycobacterium...
4.
Hansen K, Byeon C, Liu Q, Drace T, Boesen T, Conway J, et al.
Proc Natl Acad Sci U S A . 2024 Aug; 121(33):e2406775121. PMID: 39116134
Biofilm-protected pathogenic causes chronic infections that are difficult to treat. An essential building block of these biofilms are functional amyloid fibrils that assemble from phenol-soluble modulins (PSMs). PSMα1 cross-seeds other...
5.
Byeon C, Hansen K, Jeffrey J, Saricayir H, Andreasen M, Akbey U
FEBS J . 2024 Feb; 291(9):1925-1943. PMID: 38349812
Functional bacterial amyloids play a crucial role in the formation of biofilms, which mediate chronic infections and contribute to antimicrobial resistance. This study focuses on the FapC amyloid fibrillar protein...
6.
Kristoffersen K, Hansen K, Andreasen M
Int J Mol Sci . 2024 Jan; 25(1). PMID: 38203273
Phenol-soluble modulins (PSMs) are key virulence factors of , and they comprise the structural scaffold of biofilm as they self-assemble into functional amyloids. They have been shown to interact with...