Karthik Damodaran
Overview
Explore the profile of Karthik Damodaran including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
183
Followers
0
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Recent Articles
1.
Yang K, Belyaeva A, Venkatachalapathy S, Damodaran K, Katcoff A, Radhakrishnan A, et al.
Nat Commun
. 2021 Jan;
12(1):31.
PMID: 33397893
The development of single-cell methods for capturing different data modalities including imaging and sequencing has revolutionized our ability to identify heterogeneous cell states. Different data modalities provide different perspectives on...
2.
Yang K, Damodaran K, Venkatachalapathy S, Soylemezoglu A, Shivashankar G, Uhler C
PLoS Comput Biol
. 2020 Apr;
16(4):e1007828.
PMID: 32343706
Lineage tracing involves the identification of all ancestors and descendants of a given cell, and is an important tool for studying biological processes such as development and disease progression. However,...
3.
Damodaran K, Crestani M, Jokhun D, Shivashankar G
PLoS One
. 2019 Jul;
14(7):e0218757.
PMID: 31314779
Current cancer diagnosis involves the use of nuclear morphology and chromatin condensation signatures for accurate advanced stage classification. While such diagnostic approaches rely on high resolution imaging of the cell...
4.
Damodaran K, Venkatachalapathy S, Alisafaei F, Radhakrishnan A, Jokhun D, Shenoy V, et al.
Mol Biol Cell
. 2018 Sep;
29(25):3039-3051.
PMID: 30256731
Fibroblasts exhibit heterogeneous cell geometries in tissues and integrate both mechanical and biochemical signals in their local microenvironment to regulate genomic programs via chromatin remodelling. While in connective tissues fibroblasts...
5.
Radhakrishnan A, Damodaran K, Soylemezoglu A, Uhler C, Shivashankar G
Sci Rep
. 2017 Dec;
7(1):17946.
PMID: 29263424
Current cancer diagnosis employs various nuclear morphometric measures. While these have allowed accurate late-stage prognosis, early diagnosis is still a major challenge. Recent evidence highlights the importance of alterations in...