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Karsten Brand

Explore the profile of Karsten Brand including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 1246
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Recent Articles
1.
Sabel B, Brand K, Rueckel J, Hoppe B, Fink N, Bartling S
Acta Radiol . 2020 Aug; 62(7):882-889. PMID: 32772706
Background: Macrophages engulf particulate contrast media, which is pivotal for biomedical imaging. Purpose: To introduce a macrophage ablation animal model by showing its power to manipulate the kinetics of imaging...
2.
Kumar A, Cherukumilli M, Mahmoudpour S, Brand K, Bandapalli O
Biochem Biophys Res Commun . 2018 Apr; 500(3):731-737. PMID: 29679563
CXCL8 belongs to proinflammatory chemokines that are predominantly involved in neutrophil chemotaxis and degranulation. Several studies have suggested that secretion of CXCL8 from cancer cells have a profound effect on...
3.
Halama N, Zoernig I, Berthel A, Kahlert C, Klupp F, Suarez-Carmona M, et al.
Cancer Cell . 2016 Apr; 29(4):587-601. PMID: 27070705
The immune response influences the clinical course of colorectal cancer (CRC). Analyzing the invasive margin of human CRC liver metastases, we identified a mechanism of immune cell exploitation by tumor...
4.
Ganten M, Schuessler M, Bauerle T, Muenter M, Schlemmer H, Jensen A, et al.
Cancer Imaging . 2013 Dec; 13(4):548-56. PMID: 24334520
Purpose: The aim of this study was to characterize and understand the therapy-induced changes in diffusion parameters in rectal carcinoma under chemoradiotherapy (CRT). The current literature shows conflicting results in...
5.
Reissfelder C, Brand K, Sobiegalla J, Rahbari N, Bork U, Schirmacher P, et al.
Surgery . 2013 Dec; 155(2):245-54. PMID: 24314883
Background: Advances in neoadjuvant therapy enabled novel strategies for treating resectable and initially unresectable colorectal cancer liver metastases. Although it is well known that chemotherapeutic agents cause certain types of...
6.
Halama N, Spille A, Lerchl T, Brand K, Herpel E, Welte S, et al.
Oncoimmunology . 2013 Jun; 2(4):e24116. PMID: 23734335
The immune system plays an important role in shaping the clinical course of colorectal cancer (CRC). However, it is still unclear how the immune infiltrates of primary CRC lesions and...
7.
Keim S, Zoernig I, Spille A, Lahrmann B, Brand K, Herpel E, et al.
Oncoimmunology . 2012 Aug; 1(5):593-599. PMID: 22934251
The role of the immune system in the course of colorectal cancer has been elucidated in the last decade. While quantification of immune cell infiltrates within the resected specimen at...
8.
Bandapalli O, Macher-Goeppinger S, Schirmacher P, Brand K
Clin Exp Metastasis . 2012 Feb; 29(5):409-17. PMID: 22362252
In a nude mouse model of colorectal liver metastases, we have identified a paracrine tumor cell/host cell signalling pathway that is apparently required for successful tumor growth. Whereas recombinant platelet...
9.
Bandapalli O, Paul E, Schirmacher P, Brand K
BMC Res Notes . 2012 Jan; 5:14. PMID: 22230683
Background: Tissue inhibitors of metalloproteinases (TIMPs) and the corresponding metalloproteinases are integral parts of the protease network and have been shown to be involved in cancer development and metastasis. Paradoxically,...
10.
Bandapalli O, Ehrmann F, Ehemann V, Gaida M, Macher-Goeppinger S, Wente M, et al.
Cytokine . 2011 Dec; 57(1):46-53. PMID: 22129625
As part of ongoing studies to obtain a global picture of invasion related events in colorectal liver metastases, here, we report our findings on gene expression of the pro-angiogenic subgroup...