Karol S Balderrama
Overview
Explore the profile of Karol S Balderrama including associated specialties, affiliations and a list of published articles.
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10
Citations
341
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Recent Articles
1.
Jones M, Sun D, Min K, Colgan W, Tian L, Weir J, et al.
bioRxiv
. 2024 Nov;
PMID: 39484491
Tumor progression is driven by dynamic interactions between cancer cells and their surrounding microenvironment. Investigating the spatiotemporal evolution of tumors can provide crucial insights into how intrinsic changes within cancer...
2.
Russell A, Weir J, Nadaf N, Shabet M, Kumar V, Kambhampati S, et al.
Nature
. 2023 Dec;
625(7994):E11.
PMID: 38110579
No abstract available.
3.
Russell A, Weir J, Nadaf N, Shabet M, Kumar V, Kambhampati S, et al.
Nature
. 2023 Dec;
625(7993):101-109.
PMID: 38093010
Recent technological innovations have enabled the high-throughput quantification of gene expression and epigenetic regulation within individual cells, transforming our understanding of how complex tissues are constructed. However, missing from these...
4.
Langlieb J, Sachdev N, Balderrama K, Nadaf N, Raj M, Murray E, et al.
Nature
. 2023 Dec;
624(7991):333-342.
PMID: 38092915
The function of the mammalian brain relies upon the specification and spatial positioning of diversely specialized cell types. Yet, the molecular identities of the cell types and their positions within...
5.
Lake B, Menon R, Winfree S, Hu Q, Ferreira R, Kalhor K, et al.
Nature
. 2023 Jul;
619(7970):585-594.
PMID: 37468583
Understanding kidney disease relies on defining the complexity of cell types and states, their associated molecular profiles and interactions within tissue neighbourhoods. Here we applied multiple single-cell and single-nucleus assays...
6.
Russell A, Weir J, Nadaf N, Shabet M, Kumar V, Kambhampati S, et al.
bioRxiv
. 2023 Apr;
PMID: 37066158
Recent technological innovations have enabled the high-throughput quantification of gene expression and epigenetic regulation within individual cells, transforming our understanding of how complex tissues are constructed. Missing from these measurements,...
7.
Langlieb J, Sachdev N, Balderrama K, Nadaf N, Raj M, Murray E, et al.
bioRxiv
. 2023 Mar;
PMID: 36945580
The function of the mammalian brain relies upon the specification and spatial positioning of diversely specialized cell types. Yet, the molecular identities of the cell types, and their positions within...
8.
Roayapalley P, Dimmock J, Contreras L, Balderrama K, Aguilera R, Sakagami H, et al.
Molecules
. 2021 Dec;
26(23).
PMID: 34885719
A novel series of 1-[3-{3,5-bis(benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone oximes - and related quaternary ammonium salts - were prepared as candidate antineoplastic agents. Evaluation against neoplastic Ca9-22, HSC-2 and HSC-4 cells revealed the compounds...
9.
Gutierrez D, DeJesus R, Contreras L, Rodriguez-Palomares I, Villanueva P, Balderrama K, et al.
Cell Biol Toxicol
. 2019 Mar;
35(6):503-519.
PMID: 30825052
In the last 15 years, pyridazinone derivatives have acquired extensive attention due to their widespread biological activities and pharmacological applications. Pyridazinones are well known for their anti-microbial, anti-viral, anti-inflammatory, anti-cancer,...
10.
Li A, Lee C, Hurley A, Jarrett K, De Giorgi M, Lu W, et al.
Mol Ther Methods Clin Dev
. 2019 Jan;
12:111-122.
PMID: 30619914
Adeno-associated viral (AAV) vectors packaging the CRISPR-Cas9 system (AAV-CRISPR) can efficiently modify disease-relevant genes in somatic tissues with high efficiency. AAV vectors are a preferred delivery vehicle for tissue-directed gene...