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Karl Kohrer

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Articles 128
Citations 1632
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Recent Articles
11.
Bouvain P, Ding Z, Kadir S, Kleimann P, Kluge N, Tiren Z, et al.
Nat Cardiovasc Res . 2024 Aug; 2(2):126-143. PMID: 39196054
Neutrophils play a complex role during onset of tissue injury and subsequent resolution and healing. To assess neutrophil dynamics upon cardiovascular injury, here we develop a non-invasive, background-free approach for...
12.
Bogun L, Koch A, Scherer B, Germing U, Fenk R, Maus U, et al.
Cancers (Basel) . 2024 Jun; 16(11). PMID: 38893194
Myeloid and lymphoid neoplasms share the characteristics of potential bone marrow infiltration as a primary or secondary effect, which readily leads to hematopoietic insufficiency. The mechanisms by which clonal malignant...
13.
Stephan A, Suhrmann J, Skowron M, Che Y, Poschmann G, Petzsch P, et al.
Matrix Biol . 2024 Jun; 132:10-23. PMID: 38851302
Germ cell tumors (GCT) are the most common solid tumors in young men of age 15 - 40. In previous studies, we profiled the interaction of GCT cells with cells...
14.
Longo Y, Moreno Mascaraque S, Andreacchio G, Werner J, Katahira I, De Marchi E, et al.
Front Immunol . 2024 May; 15:1360140. PMID: 38711513
Introduction: Modified Vaccinia Virus Ankara (MVA) is a safe vaccine vector inducing long- lasting and potent immune responses. MVA-mediated CD8T cell responses are optimally induced, if both, direct- and cross-presentation...
15.
Muller M, Burmeister A, Skowron M, Stephan A, Sohngen C, Wollnitzke P, et al.
Exp Cell Res . 2024 May; 439(1):114055. PMID: 38704080
Background: Being implicated during tumor migration, invasion, clonogenicity, and proliferation, the nicotinamide adenine dinucleotide (NAD)/-phosphate (NADP)-dependent dehydrogenase/reductase member 2 (DHRS2) has been considered to be induced upon inhibition of histone...
16.
Meneceur S, De Vos C, Petzsch P, Kohrer K, Niegisch G, Hoffmann M
J Cell Mol Med . 2024 May; 28(9):e18342. PMID: 38693852
Urothelial carcinoma (UC) urgently requires new therapeutic options. Histone deacetylases (HDAC) are frequently dysregulated in UC and constitute interesting targets for the development of alternative therapy options. Thus, we investigated...
17.
Rafii P, Cruz P, Ettich J, Seibel C, Padrini G, Wittich C, et al.
J Biol Chem . 2024 Apr; 300(5):107251. PMID: 38569939
Ciliary neurotrophic factor (CNTF) activates cells via the non-signaling α-receptor CNTF receptor (CNTFR) and the two signaling β-receptors glycoprotein 130 (gp130) and leukemia inhibitory factor receptor (LIFR). The CNTF derivate,...
18.
Bogun L, Koch A, Scherer B, Fenk R, Maus U, Bormann F, et al.
Blood Adv . 2024 Jan; 8(10):2575-2588. PMID: 38241490
The hallmark of multiple myeloma (MM) is a clonal plasma cell infiltration in the bone marrow accompanied by myelosuppression and osteolysis. Premalignant stages such as monoclonal gammopathy of undetermined significance...
19.
Schiavi A, Cirotti C, Gerber L, Di Lauro G, Maglioni S, Shibao P, et al.
Cell Death Discov . 2023 Oct; 9(1):376. PMID: 37838776
Alzheimer's disease is the most common age-associated neurodegenerative disorder and the most frequent form of dementia in our society. Aging is a complex biological process concurrently shaped by genetic, dietary...
20.
Frerichs L, Frerichs B, Petzsch P, Kohrer K, Windolf J, Bittersohl B, et al.
Front Oncol . 2023 Oct; 13:1228185. PMID: 37781195
Background: Patients with muscle-invasive bladder cancer face a poor prognosis due to rapid disease progression and chemoresistance. Thus, there is an urgent need for a new therapeutic treatment. The tumor...