Karl Clauser
Overview
Explore the profile of Karl Clauser including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
14
Citations
784
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Phulphagar K, Ctortecka C, Jacome A, Klaeger S, Verzani E, Hernandez G, et al.
bioRxiv
. 2023 Mar;
PMID: 36993564
Comprehensive, in-depth identification of the human leukocyte antigen HLA-I and HLA-II tumor immunopeptidome can inform the development of cancer immunotherapies. Mass spectrometry (MS) is powerful technology for direct identification of...
2.
Dou Y, Kawaler E, Zhou D, Gritsenko M, Huang C, Blumenberg L, et al.
Cell
. 2020 Feb;
180(4):729-748.e26.
PMID: 32059776
We undertook a comprehensive proteogenomic characterization of 95 prospectively collected endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This analysis revealed possible new consequences of perturbations to the p53...
3.
Mullahoo J, Zhang T, Clauser K, Carr S, Jaffe J, Papanastasiou M
Methods
. 2020 Feb;
184:135-140.
PMID: 32004545
The N-terminal regions of histone proteins (tails) are dynamic elements that protrude from the nucleosome and are involved in many aspects of chromatin organization. Their epigenetic role is well-established, and...
4.
Binz P, Shofstahl J, Vizcaino J, Barsnes H, Chalkley R, Menschaert G, et al.
J Proteome Res
. 2019 May;
18(6):2686-2692.
PMID: 31081335
Mass-spectrometry-based proteomics enables the high-throughput identification and quantification of proteins, including sequence variants and post-translational modifications (PTMs) in biological samples. However, most workflows require that such variations be included in...
5.
Myers S, Klaeger S, Satpathy S, Viner R, Choi J, Rogers J, et al.
J Proteome Res
. 2018 Oct;
18(1):542-547.
PMID: 30351145
Tandem mass tag (TMT)-based quantitation is a strong modality for quantitative proteomics, as samples can be multiplexed, creating large-scale data sets with high precision and minimal missing values. However, coisolation/cofragmentation...
6.
Archer T, Ehrenberger T, Mundt F, Gold M, Krug K, Mah C, et al.
Cancer Cell
. 2018 Sep;
34(3):396-410.e8.
PMID: 30205044
There is a pressing need to identify therapeutic targets in tumors with low mutation rates such as the malignant pediatric brain tumor medulloblastoma. To address this challenge, we quantitatively profiled...
7.
Udeshi N, Pedram K, Svinkina T, Fereshetian S, Myers S, Aygun O, et al.
Nat Methods
. 2017 Oct;
14(12):1167-1170.
PMID: 29039416
Although purification of biotinylated molecules is highly efficient, identifying specific sites of biotinylation remains challenging. We show that anti-biotin antibodies enable unprecedented enrichment of biotinylated peptides from complex peptide mixtures....
8.
Mertins P, Przybylski D, Yosef N, Qiao J, Clauser K, Raychowdhury R, et al.
Cell Rep
. 2017 Jun;
19(13):2853-2866.
PMID: 28658630
Building an integrated view of cellular responses to environmental cues remains a fundamental challenge due to the complexity of intracellular networks in mammalian cells. Here, we introduce an integrative biochemical...
9.
Hahn C, Berchuck J, Ross K, Kakoza R, Clauser K, Schinzel A, et al.
Cancer Cell
. 2009 Oct;
16(4):281-94.
PMID: 19800574
Cell-based screening can facilitate the rapid identification of compounds inducing complex cellular phenotypes. Advancing a compound toward the clinic, however, generally requires the identification of precise mechanisms of action. We...
10.
Addona T, Clauser K
Curr Protoc Protein Sci
. 2008 Apr;
Chapter 16:Unit 16.11.
PMID: 18429223
Databases of complete genome sequences are rapidly appearing, and a recent trend in interpretation of peptide MS/MS spectra is database matching. A caveat of database matching is that it can...