Karin L Gustafsson
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Explore the profile of Karin L Gustafsson including associated specialties, affiliations and a list of published articles.
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18
Citations
169
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Recent Articles
1.
Scheffler J, Gustafsson K, Barrett A, Corciulo C, Drevinge C, Del Carpio Pons A, et al.
JBMR Plus
. 2022 Aug;
6(8):e10657.
PMID: 35991530
Estrogen has pronounced effects on the immune system, which also influences bone homeostasis. In recent years, stromal cells in lymphoid organs have gained increasing attention as they not only support...
2.
Gustafsson K, Moverare-Skrtic S, Farman H, Engdahl C, Henning P, Nilsson K, et al.
J Endocrinol
. 2022 Mar;
253(2):75-84.
PMID: 35256537
Selective estrogen receptor modulators (SERMs) act as estrogen receptor (ER) agonists or antagonists in a tissue-specific manner. ERs exert effects via nuclear actions but can also utilize membrane-initiated signaling pathways....
3.
Lawenius L, Gustafsson K, Wu J, Nilsson K, Moverare-Skrtic S, Schott E, et al.
Am J Physiol Endocrinol Metab
. 2022 Feb;
322(4):E344-E354.
PMID: 35156423
The gut microbiome has the capacity to regulate bone mass. The aim of this study was to develop a nutritional synbiotic dietary assemblage at an optimal dose to maintain bone...
4.
Nilsson K, Wu J, Gustafsson K, El Shahawy M, Koskela A, Tuukkanen J, et al.
Am J Physiol Endocrinol Metab
. 2022 Jan;
322(3):E211-E218.
PMID: 35068191
Osteoporosis is an age-dependent serious skeletal disease that leads to great suffering for the patient and high social costs, especially as the global population reaches higher age. Decreasing estrogen levels...
5.
Nordqvist J, Engdahl C, Scheffler J, Gupta P, Gustafsson K, Lagerquist M, et al.
Lupus
. 2022 Jan;
31(2):143-154.
PMID: 35062848
Osteoporosis is a common secondary complication in patients with systemic lupus erythematosus (SLE). Current osteoporosis treatment with bisphosphonates has some negative side effects and there is a lack of data...
6.
Collden H, Nilsson M, Norlen A, Landin A, Windahl S, Wu J, et al.
Endocrinology
. 2022 Jan;
163(3).
PMID: 34999782
A comprehensive atlas of sex steroid distribution in multiple tissues is currently lacking, and how circulating and tissue sex steroid levels correlate remains unknown. Here, we adapted and validated a...
7.
Corciulo C, Scheffler J, Gustafsson K, Drevinge C, Humeniuk P, Del Carpio Pons A, et al.
F1000Res
. 2021 Dec;
10:809.
PMID: 34868559
Estrogens are important regulators of body physiology and have major effects on metabolism, bone, the immune- and central nervous systems. The specific mechanisms underlying the effects of estrogens on various...
8.
Nilsson K, Henning P, El Shahawy M, Nethander M, Andersen T, Ejersted C, et al.
Nat Commun
. 2021 Aug;
12(1):4923.
PMID: 34389713
With increasing age of the population, countries across the globe are facing a substantial increase in osteoporotic fractures. Genetic association signals for fractures have been reported at the RSPO3 locus,...
9.
Lagerquist M, Gustafsson K, Henning P, Farman H, Wu J, Sjogren K, et al.
Sci Rep
. 2021 Jul;
11(1):14177.
PMID: 34238965
Obesity has previously been thought to protect bone since high body weight and body mass index are associated with high bone mass. However, some more recent studies suggest that increased...
10.
Gustafsson K, Farman H, Nilsson K, Henning P, Moverare-Skrtic S, Lionikaite V, et al.
Am J Physiol Endocrinol Metab
. 2020 Nov;
320(1):E160-E168.
PMID: 33225718
Mutation of arginine 264 in ERα has been shown to abrogate rapid membrane ERα-mediated endothelial effects. Our novel finding that mutation of R264 is dispensable for ERα-mediated skeletal effects supports...