Karin Kipper
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Explore the profile of Karin Kipper including associated specialties, affiliations and a list of published articles.
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354
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Recent Articles
1.
Odhiambo M, Kaingu G, Mumbo M, Kipper K, Sander J, Newton C, et al.
Epilepsy Behav
. 2024 Dec;
163:110215.
PMID: 39671739
Purpose: Managing epilepsy may require using more than one anti-seizure medication (ASM). While combination therapy may help, risks, including psychiatric problems, are not fully explored in Africa. We examined the...
2.
Padari H, Kipper K, Eelmae I, Nerman J, Lintrop M, Metsvaht T
Clin Case Rep
. 2024 Apr;
12(4):e8676.
PMID: 38585587
Treatment of congenital chyloperitoneum is a challenge. Conservative methods may be ineffective. Preoperative visualization of the site of lymphatic leakage is crucial, but radiological imaging is technically complicated and may...
3.
Lass J, Leroux S, Korgvee L, Varendi H, Kipper K, Takkis K, et al.
Eur J Clin Pharmacol
. 2023 Dec;
80(2):239-248.
PMID: 38041740
Purpose: Spironolactone is a potassium sparing diuretic used for decades. Until now, pharmacokinetic (PK) studies of spironolactone have not been conducted in infants and therefore pediatric dosing is based on...
4.
Soeorg H, Padari H, Ilmoja M, Herodes K, Kipper K, Lutsar I, et al.
Br J Clin Pharmacol
. 2023 Oct;
90(3):801-811.
PMID: 37903648
Aims: C-reactive protein (CRP) is used to determine the effect of antibiotic treatment on sepsis in neonates/infants. We aimed to develop pharmacokinetic-pharmacodynamic (PKPD) model of meropenem and CRP in neonates/infants...
5.
Barker C, Kipper K, Lonsdale D, Wright K, Thompson G, Kim M, et al.
J Antimicrob Chemother
. 2023 Aug;
78(9):2148-2161.
PMID: 37531085
Background: Pharmacokinetic (PK) data underlying paediatric penicillin dosing remain limited, especially in critical care. Objectives: The primary objective of the Neonatal and Paediatric Pharmacokinetics of Antimicrobials study (NAPPA) was to...
6.
Shah R, Kipper K, Baker E, Barker C, Oldfield I, Philips B, et al.
Antibiotics (Basel)
. 2023 Apr;
12(4).
PMID: 37107004
Pharmacokinetics are highly variable in critical illness, and suboptimal antibiotic exposure is associated with treatment failure. Benzylpenicillin is a commonly used beta-lactam antibiotic, and pharmacokinetic data of its use in...
7.
Antunes N, Moreira F, Kipper K, Couchman L, Lebre D, Johnston A, et al.
Pharmaceuticals (Basel)
. 2023 Jan;
16(1).
PMID: 36678526
This study predicted dapaconazole clinical drug−drug interactions (DDIs) over the main Cytochrome P450 (CYP) isoenzymes using static (in vitro to in vivo extrapolation equation, IVIVE) and dynamic (PBPK model) approaches....
8.
Kloprogge F, Canseco J, Phee L, Sadouki Z, Kipper K, Witney A, et al.
Sci Rep
. 2022 Dec;
12(1):21429.
PMID: 36504241
Concentration dependency of phenotypic and genotypic isoniazid-rifampicin resistance emergence was investigated to obtain a mechanistic understanding on how anti-mycobacterial drugs facilitate the emergence of bacterial populations that survive throughout treatment....
9.
Antunes N, Coombes G, da Cunha K, Moreira F, Pilon A, Lopes N, et al.
Drug Metab Pharmacokinet
. 2022 Nov;
47:100475.
PMID: 36370616
Dapaconazole is a new antifungal imidazole that has been shown a high efficacy against several pathogenic fungi. This study aimed to investigate the interspecies variation in the in vitro metabolic...
10.
Soeorg H, Padari H, Kipper K, Ilmoja M, Lutsar I, Metsvaht T
AAPS J
. 2022 Jun;
24(4):77.
PMID: 35760955
Gentamicin is a commonly used antibiotic in neonates. Its components C1, C1a, C2, C2a, and C2b may have different nephrotoxic potential. We aimed to describe pharmacokinetics and nephrotoxic potential of...