Karen R Jacobson
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Explore the profile of Karen R Jacobson including associated specialties, affiliations and a list of published articles.
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62
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922
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Recent Articles
1.
Wijk M, Wasmann R, Jacobson K, Svensson E, Denti P
CPT Pharmacometrics Syst Pharmacol
. 2025 Mar;
PMID: 40067154
Proper handling of data below the lower limit of quantification (BLQ) is crucial for accurate pharmacokinetic parameter estimation. The M3 method proposed by Beal uses a likelihood-based approach that is...
2.
Tzelios C, Malatesta S, Carney T, White L, Weber S, Thomson S, et al.
Clin Infect Dis
. 2025 Feb;
PMID: 39973802
Background: Adverse drug reactions (ADRs) to tuberculosis (TB) medications make treatment completion challenging. We investigated the impact of alcohol, human immunodeficiency virus (HIV), and other patient determinants on ADRs and...
3.
Murnane P, Afshar M, Chamie G, Cook R, Ferguson T, Haque L, et al.
Am J Gastroenterol
. 2024 Oct;
PMID: 39480054
Introduction: Accurate assessment of alcohol use informs prevention and management of liver disease. We examined whether phosphatidylethanol (PEth, an alcohol metabolite) blood concentrations are associated with liver fibrosis risk independently...
4.
Overbeck V, Malatesta S, Carney T, Myers B, Parry C, Horsburgh C, et al.
BMC Infect Dis
. 2024 Oct;
24(1):1154.
PMID: 39396938
Background: The COVID-19 pandemic negatively impacted tuberculosis (TB) treatment services, including directly observed therapy (DOT) programs used to promote medication adherence. We compared DOT adherence embedded in a research study...
5.
Campbell J, Lavache D, Garing A, Sabharwal V, Haberer J, Dubois M, et al.
Open Forum Infect Dis
. 2024 Sep;
11(9):ofae494.
PMID: 39238842
In the United States, tuberculosis (TB) screening is recommended for pregnant individuals with TB risk factors. We conducted a retrospective study of perinatal TB infection testing and treatment in a...
6.
Ghanem M, Srivastava R, Ektefaie Y, Hoppes D, Rosenfeld G, Yaniv Z, et al.
medRxiv
. 2024 Sep;
PMID: 39228708
One Sentence Summary: The percent of lung involved in disease improves prediction of unfavorable outcomes in pulmonary tuberculosis when added to clinical characteristics.
7.
Kulkarni S, Weber S, Buys C, Lambrechts T, Myers B, Drainoni M, et al.
BMC Public Health
. 2024 Aug;
24(1):2216.
PMID: 39143513
Background: Unhealthy alcohol use is widespread in South Africa and has been linked to tuberculosis (TB) disease and poor treatment outcomes. This study used qualitative methods to explore the relationship...
8.
Wijk M, Gausi K, Malatesta S, Weber S, Court R, Myers B, et al.
J Antimicrob Chemother
. 2024 Jul;
79(8):2022-2030.
PMID: 38985541
Background: In South Africa, an estimated 11% of the population have high alcohol use, a major risk factor for TB. Alcohol and other substance use are also associated with poor...
9.
Marin M, Wippel C, Quinones-Olvera N, Behruznia M, Jeffrey B, Harris M, et al.
bioRxiv
. 2024 Apr;
PMID: 38585972
Pan-genome analysis is a fundamental tool for studying bacterial genome evolution; however, the variety of methods used to define and measure the pan-genome poses challenges to the interpretation and reliability...
10.
Shapiro A, Scott L, Moultrie H, Jacobson K, Bor J, Fofana A, et al.
Sci Rep
. 2023 Nov;
13(1):20875.
PMID: 38012266
The National Health Laboratory Service (NHLS) collects all public health laboratory test results in South Africa, providing a cohort from which to identify groups, by age, sex, HIV, and viral...