Karen McLean
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Explore the profile of Karen McLean including associated specialties, affiliations and a list of published articles.
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86
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2768
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Recent Articles
1.
Sliwka J, Wasilewicz-Flis I, Jakuczun H, Janiszewska M, Smyda-Dajmund P, McLean K, et al.
Planta
. 2025 Feb;
261(4):69.
PMID: 40014142
Using a diploid potato diversity panel of 246 breeding lines, a genotyping-by-sequencing and a GWAS approach, we mapped QTL for ten traits important to potato breeders, including two previously unmapped...
2.
Dommer A, Kumarasamy V, Wang J, OConnor T, Roti M, Mahan S, et al.
Cancer Res
. 2025 Feb;
PMID: 39945638
CDK2 inhibitors have recently been developed and entered clinical trials. Combination approaches can help broaden the use of therapeutic agents and establish more effective treatments. Here, we evaluated the selective...
3.
Kumarasamy V, Wang J, Roti M, Wan Y, Dommer A, Rosenheck H, et al.
Nat Commun
. 2025 Feb;
16(1):1476.
PMID: 39924553
Cyclin dependent kinase 2 (CDK2) regulates cell cycle and is an emerging target for cancer therapy. There are relatively small numbers of tumor models that exhibit strong dependence on CDK2...
4.
Tondo-Steele K, Milliron K, Siedel J, Uppal S, Merajver S, McLean K
Gynecol Oncol Rep
. 2024 Sep;
55:101498.
PMID: 39297075
An increase in the risk of developing uterine serous carcinoma (USC) has been observed among and germline pathogenic variant carriers in the published literature. However, routine germline genetic testing is...
5.
Nakatsuka E, Tan L, Cunneen B, Foster C, Lei Y, McLean K
Transl Oncol
. 2024 Sep;
50:102119.
PMID: 39270525
While poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) have improved the prognosis of ovarian high-grade serous carcinoma (HGSC) tumors that are homologous recombination (HR) deficient (HRD), new therapeutic strategies are needed...
6.
Manorot A, Uppal S, de Bear O, Stroup C, Dalton L, Rolston A, et al.
Int J Gynecol Cancer
. 2024 Aug;
34(9):1431-1436.
PMID: 39122446
Objective: To determine the rate of avoidable admissions following anticipated same-day discharge for patients undergoing minimally invasive hysterectomy and to identify risk factors associated with such admissions. Methods: A retrospective...
7.
Alimujiang A, Strecher V, McLean K, Mondul A, Pearce C, Mukherjee B
Soc Psychiatry Psychiatr Epidemiol
. 2024 Jul;
PMID: 39044017
Purpose: This study quantified the effect of 48 psychosocial constructs on all-cause mortality using data from 7,698 individuals in the U.S. Health and Retirement Study. Methods: Latent class analysis was...
8.
Sharma S, McLean K, Hedley P, Dale F, Daniels S, Bryan G
Theor Appl Genet
. 2024 Jul;
137(8):180.
PMID: 38980417
De novo genotyping in potato using methylation-sensitive GBS discovers SNPs largely confined to genic or gene-associated regions and displays enhanced effectiveness in estimating LD decay rates, population structure and detecting...
9.
Leuenberger J, Sharma S, McLean K, Pelle R, Berard A, Lesage M, et al.
Front Plant Sci
. 2024 Jun;
15():1384401.
PMID: 38828224
No abstract available.
10.
Straubhar A, Stroup C, Manorot A, McCool K, Rolston A, Reynolds R, et al.
Int J Gynecol Cancer
. 2024 Apr;
34(5):745-750.
PMID: 38642924
Background: The potential for the technique of small bite fascial closure in mitigating incisional hernias in gynecologic oncology patients still needs to be investigated. Objective: To evaluate the impact of...