Karen J Tonsfeldt
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Explore the profile of Karen J Tonsfeldt including associated specialties, affiliations and a list of published articles.
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28
Citations
409
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Recent Articles
1.
Tchoe Y, Wu T, U H, Roth D, Kim D, Lee J, et al.
Sci Transl Med
. 2024 Apr;
16(744):eadj7257.
PMID: 38657026
Functional mapping during brain surgery is applied to define brain areas that control critical functions and cannot be removed. Currently, these procedures rely on verbal interactions between the neurosurgeon and...
2.
Lee K, Paulk A, Ro Y, Cleary D, Tonsfeldt K, Kfir Y, et al.
Nat Commun
. 2024 Jan;
15(1):218.
PMID: 38233418
Over the past decade, stereotactically placed electrodes have become the gold standard for deep brain recording and stimulation for a wide variety of neurological and psychiatric diseases. Current electrodes, however,...
3.
Van Loh B, Yaw A, Breuer J, Jackson B, Nguyen D, Jang K, et al.
Front Endocrinol (Lausanne)
. 2024 Jan;
14:1269672.
PMID: 38205198
Background: The suprachiasmatic nucleus (SCN) within the hypothalamus is a key brain structure required to relay light information to the body and synchronize cell and tissue level rhythms and hormone...
4.
Tan H, Paulk A, Stedelin B, Cleary D, Nerison C, Tchoe Y, et al.
J Neurosurg
. 2023 Oct;
140(3):665-676.
PMID: 37874692
Objective: The study objective was to evaluate intraoperative experience with newly developed high-spatial-resolution microelectrode grids composed of poly(3,4-ethylenedioxythiophene) with polystyrene sulfonate (PEDOT:PSS), and those composed of platinum nanorods (PtNRs). Methods:...
5.
Tchoe Y, Wu T, U H, Roth D, Kim D, Lee J, et al.
bioRxiv
. 2023 Jul;
PMID: 37503216
Brain surgeries are among the most delicate clinical procedures and must be performed with the most technologically robust and advanced tools. When such surgical procedures are performed in functionally critical...
6.
Vatsyayan R, Lee J, Bourhis A, Tchoe Y, Cleary D, Tonsfeldt K, et al.
MRS Bull
. 2023 Jul;
48(5):531-546.
PMID: 37476355
Electrophysiological recording and stimulation are the gold standard for functional mapping during surgical and therapeutic interventions as well as capturing cellular activity in the intact human brain. A critical component...
7.
Cassin J, Stamou M, Keefe K, Sung K, Bojo C, Tonsfeldt K, et al.
JCI Insight
. 2023 Jan;
8(3).
PMID: 36602867
Pathogenic SRY-box transcription factor 2 (SOX2) variants typically cause severe ocular defects within a SOX2 disorder spectrum that includes hypogonadotropic hypogonadism. We examined exome-sequencing data from a large, well-phenotyped cohort...
8.
Siler D, Cleary D, Tonsfeldt K, Wali A, Hinson H, Khalessi A, et al.
Oper Neurosurg (Hagerstown)
. 2022 Dec;
24(1):80-87.
PMID: 36519881
Background: Systematic use of neurosurgical training simulators across institutions is significantly hindered by logistical and financial constraints. Objective: To evaluate feasibility of large-scale implementation of an intraoperative catastrophe simulation, we...
9.
Lee S, Thunemann M, Lee K, Cleary D, Tonsfeldt K, Oh H, et al.
Adv Funct Mater
. 2022 Nov;
32(25).
PMID: 36381629
The Utah array powers cutting-edge projects for restoration of neurological function, such as BrainGate, but the underlying electrode technology has itself advanced little in the last three decades. Here, advanced...
10.
Tonsfeldt K, Cui L, Lee J, Walbeek T, Brusman L, Jin Y, et al.
Front Endocrinol (Lausanne)
. 2022 Aug;
13:956169.
PMID: 35992114
Disruptions to the circadian system alter reproductive capacity, particularly in females. Mice lacking the core circadian clock gene, , are infertile and have evidence of neuroendocrine disruption including the absence...