Karen Chew
Overview
Explore the profile of Karen Chew including associated specialties, affiliations and a list of published articles.
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15
Citations
1599
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Recent Articles
1.
Kerlikowske K, Molinaro A, Gauthier M, Berman H, Waldman F, Bennington J, et al.
J Natl Cancer Inst
. 2010 Apr;
102(9):627-37.
PMID: 20427430
Background: Studies have failed to identify characteristics of women who have been diagnosed with ductal carcinoma in situ (DCIS) and have a high or low risk of subsequent invasive cancer....
2.
Tutt A, Wang A, Rowland C, Gillett C, Lau K, Chew K, et al.
BMC Cancer
. 2008 Nov;
8:339.
PMID: 19025599
Background: Given the large number of genes purported to be prognostic for breast cancer, it would be optimal if the genes identified are not confounded by the continuously changing systemic...
3.
Park C, Rembert J, Chew K, Moore D, Kerlikowske K
Int J Radiat Oncol Biol Phys
. 2008 Aug;
73(1):75-9.
PMID: 18692323
Purpose: Biologically meaningful predictors for locoregional recurrence (LRR) in patients undergoing breast-conserving surgery (BCS) and radiotherapy (RT) are lacking. Tissue components, including extracellular matrix, could confer resistance to ionizing radiation....
4.
Gauthier M, Berman H, Miller C, Kozakeiwicz K, Chew K, Moore D, et al.
Cancer Cell
. 2007 Nov;
12(5):479-91.
PMID: 17996651
Approximately 15%-30% of women diagnosed with ductal carcinoma in situ (DCIS) develop a subsequent tumor event within 10 years after surgical lumpectomy. To date, little is known about the molecular...
5.
Yau C, Fedele V, Roydasgupta R, Fridlyand J, Hubbard A, Gray J, et al.
Breast Cancer Res
. 2007 Sep;
9(5):R59.
PMID: 17850661
Introduction: Age is one of the most important risk factors for human malignancies, including breast cancer; in addition, age at diagnosis has been shown to be an independent indicator of...
6.
Zhou Y, Yau C, Gray J, Chew K, Dairkee S, Moore D, et al.
BMC Cancer
. 2007 Apr;
7:59.
PMID: 17407600
Background: Signaling pathways that converge on two different transcription factor complexes, NFkappaB and AP-1, have been identified in estrogen receptor (ER)-positive breast cancers resistant to the antiestrogen, tamoxifen. Methods: Two...
7.
Yao E, Zhang H, Chen Y, Lee B, Chew K, Moore D, et al.
Cancer Res
. 2007 Jan;
67(2):659-64.
PMID: 17234776
Aberrant microenvironments and loss of balance in cell-extracellular matrix signaling are associated with breast cancer invasion, metastasis, and resistance to therapy. We have recently shown that increased beta1 integrin signaling...
8.
Chin K, DeVries S, Fridlyand J, Spellman P, Roydasgupta R, Kuo W, et al.
Cancer Cell
. 2006 Dec;
10(6):529-41.
PMID: 17157792
This study explores the roles of genome copy number abnormalities (CNAs) in breast cancer pathophysiology by identifying associations between recurrent CNAs, gene expression, and clinical outcome in a set of...
9.
Rini B, Jaeger E, Weinberg V, Sein N, Chew K, Fong K, et al.
BJU Int
. 2006 Jul;
98(4):756-62.
PMID: 16827904
Objective: To describe the relationship among patient characteristics, Von Hippel-Lindau (VHL) gene status and clinical outcome in metastatic renal cell carcinoma (RCC) in patients receiving vascular endothelial growth factor (VEGF)-targeted...
10.
Meng Z, Ben Y, Li Z, Chew K, Ljung B, Lagios M, et al.
Genes Chromosomes Cancer
. 2004 Aug;
41(3):214-22.
PMID: 15334544
In the search for early deletion targets in sporadic breast cancer, the analysis of TP53, BRCA1, BRCA2, and ATM revealed loss of heterozygosity (LOH) in tumor cells at 1 or...