Karen Bieback
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Explore the profile of Karen Bieback including associated specialties, affiliations and a list of published articles.
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137
Citations
5505
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Recent Articles
11.
Skovronova R, Scaccia E, Calcat-I-Cervera S, Bussolati B, OBrien T, Bieback K
J Transl Med
. 2023 Oct;
21(1):723.
PMID: 37840135
Background: Extracellular vesicles (EV) are considered a cell-free alternative to mesenchymal stromal cell (MSC) therapy. Numerous reports describe the efficacy of EV in conferring immunomodulation and promoting angiogenesis, yet others...
12.
Will P, Kilian K, Bieback K, Fricke F, Berner J, Kneser U, et al.
Plast Reconstr Surg
. 2023 Oct;
154(4):688e-700e.
PMID: 37832143
Background: The driver of secondary lymphedema (SL) progression is chronic inflammation, which promotes fibrosis. Despite advances in preclinical research, a specific effector cell subpopulation as a biomarker for therapy response...
13.
da Silva T, Rendra E, David C, Bieback K, Cross M, Wilm B, et al.
Biomed Pharmacother
. 2023 Oct;
167:115624.
PMID: 37783151
Mesenchymal stromal cells (MSCs) have been reported to display efficacy in a variety of preclinical models, but without long-term engraftment, suggesting a role for secreted factors, such as MSC-derived extracellular...
14.
Affolter A, Liebel K, Tengler L, Seiz E, Tiedtke M, Azhakesan A, et al.
Int J Oncol
. 2023 Jul;
63(3).
PMID: 37503786
Although checkpoint inhibitors (CPI) have recently extended the treatment options and improved clinical response of advanced stage head and neck squamous cell carcinoma (HNSCC), treatment success remains unpredictable. Programmed cell...
15.
Calcat-I-Cervera S, Rendra E, Scaccia E, Amadeo F, Hanson V, Wilm B, et al.
Stem Cell Res Ther
. 2023 May;
14(1):120.
PMID: 37143116
Background: Mesenchymal stromal cells (MSCs), commonly sourced from adipose tissue, bone marrow and umbilical cord, have been widely used in many medical conditions due to their therapeutic potential. Yet, the...
16.
Willer H, Spohn G, Morgenroth K, Thielemann C, Elvers-Hornung S, Bugert P, et al.
Front Immunol
. 2022 Sep;
13:976511.
PMID: 36059533
Human Mesenchymal Stromal Cells (hMSCs) are a promising source for cell-based therapies. Yet, transition to phase III and IV clinical trials is remarkably slow. To mitigate donor variabilities and to...
17.
Weber T, Wiest J, Oredsson S, Bieback K
Altern Lab Anim
. 2022 Aug;
50(5):330-338.
PMID: 35983799
Cell culture techniques are strongly connected with modern scientific laboratories and production facilities. Thus, choosing the most suitable medium for the cells involved is vital, not only directly to optimise...
18.
Fan X, Cyganek L, Nitschke K, Uhlig S, Nuhn P, Bieback K, et al.
Int J Mol Sci
. 2022 Aug;
23(15).
PMID: 35955642
Endothelial cells derived from human induced pluripotent stem cells (hiPSC-ECs) provide a new opportunity for mechanistic research on vascular regeneration and drug screening. However, functions of hiPSC-ECs still need to...
19.
Boecker C, Sitzmann N, Halblaub Miranda J, Suhr H, Wiedemann P, Bieback K, et al.
Transfus Med Hemother
. 2022 Jul;
49(3):172-179.
PMID: 35813604
Background: Transfusion of red cell concentrates (RCCs) is an integral therapy after severe hemorrhage or trauma. Prehospital transfusion offers an immediate intervention in emergency cases. Air ambulance-based prehospital transfusion, already...
20.
Affolter A, Kern J, Bieback K, Scherl C, Rotter N, Lammert A
Int J Oncol
. 2022 Jun;
61(1).
PMID: 35642667
Immunotherapy has evolved into a powerful tool in the fight against a number of types of cancer, including head and neck squamous cell carcinomas (HNSCC). Although checkpoint inhibition (CPI) has...