Kareem M Ahmad
Overview
Explore the profile of Kareem M Ahmad including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
211
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Recent Articles
1.
Walker F, Ahmad K, Eisenstein M, Soh H
Anal Chem
. 2014 Sep;
86(18):9236-41.
PMID: 25223929
Molecular diagnostics based on the polymerase chain reaction (PCR) offer rapid and sensitive means for detecting infectious disease, but prohibitive costs have impeded their use in resource-limited settings where such...
2.
Meyer S, Maufort J, Nie J, Stewart R, McIntosh B, Conti L, et al.
PLoS One
. 2013 Aug;
8(8):e71798.
PMID: 23967247
Background: DNA aptamers generated by cell-SELEX offer an attractive alternative to antibodies, but generating aptamers to specific, known membrane protein targets has proven challenging, and has severely limited the use...
3.
Ahmad K, Xiao Y, Soh H
Nucleic Acids Res
. 2012 Oct;
40(22):11777-83.
PMID: 23042245
Multivalent molecular interactions can be exploited to dramatically enhance the performance of an affinity reagent. The enhancement in affinity and specificity achieved with a multivalent construct depends critically on the...
4.
Gong Q, Wang J, Ahmad K, Csordas A, Zhou J, Nie J, et al.
Anal Chem
. 2012 May;
84(12):5365-71.
PMID: 22624874
Many analytical techniques benefit greatly from the use of affinity reagent pairs, wherein each reagent recognizes a discrete binding site on a target. For example, antibody pairs have been widely...
5.
Ahmad K, Oh S, Kim S, McClellen F, Xiao Y, Soh H
PLoS One
. 2011 Nov;
6(11):e27051.
PMID: 22110600
Nucleic acid-based aptamers offer many potential advantages relative to antibodies and other protein-based affinity reagents, including facile chemical synthesis, reversible folding, improved thermal stability and lower cost. However, their selection...
6.
Oh S, Ahmad K, Cho M, Kim S, Xiao Y, Soh H
Anal Chem
. 2011 Jul;
83(17):6883-9.
PMID: 21774453
The generation of nucleic acid aptamers with high affinity typically entails a time-consuming, iterative process of binding, separation, and amplification. It would therefore be beneficial to develop an efficient selection...
7.
Schein S, Ahmad K
Biophys J
. 2006 Aug;
91(9):3257-67.
PMID: 16920838
A rod transmits absorption of a single photon by what appears to be a small reduction in the small number of quanta of neurotransmitter (Q(count)) that it releases within the...
8.
Schein S, Ahmad K
Biophys J
. 2005 Sep;
89(6):3931-49.
PMID: 16169984
We can see at light intensities much lower than an average of one photon per rod photoreceptor, demonstrating that rods must be able to transmit a signal after absorption of...
9.
Ahmad K, Klug K, Herr S, Sterling P, Schein S
Vis Neurosci
. 2003 Aug;
20(2):189-209.
PMID: 12916740
We examine the assumptions that the fovea contains equal numbers of inner (invaginating or ON) and outer (flat or OFF) midget bipolar cells and equal numbers of inner and outer...