Kara M Foshay
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Explore the profile of Kara M Foshay including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
259
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Recent Articles
1.
Abedalthagafi M, Barakeh D, Foshay K
NPJ Precis Oncol
. 2018 Dec;
2:27.
PMID: 30534602
The prognosis of glioblastoma has changed little over the past two decades, with only minor improvements in length of overall survival through the addition of temozolomide (temodal) to standard of...
2.
Parker J, Lizarraga M, Waziri A, Foshay K
J Vis Exp
. 2017 Aug;
(125).
PMID: 28784966
Glioblastoma (GBM) continues to carry an extremely poor clinical prognosis despite surgical, chemotherapeutic, and radiation therapy. Progressive tumor invasion into surrounding brain parenchyma represents an enduring therapeutic challenge. To develop...
3.
Looney T, Zhang L, Chen C, Lee J, Chari S, Mao F, et al.
Genome Res
. 2013 Dec;
24(2):267-80.
PMID: 24310002
Both diffusible factors acting in trans and chromatin components acting in cis are implicated in gene regulation, but the extent to which either process causally determines a cell's transcriptional identity...
4.
Foshay K, Looney T, Chari S, Mao F, Lee J, Zhang L, et al.
Mol Cell
. 2012 Mar;
46(2):159-70.
PMID: 22445485
It is a long-held paradigm that cell fusion reprograms gene expression but the extent of reprogramming and whether it is affected by the cell types employed remain unknown. We recently...
5.
Gaetz J, Clift K, Fernandes C, Mao F, Lee J, Zhang L, et al.
Cell Res
. 2011 Nov;
22(5):848-58.
PMID: 22124232
The progressive restriction of cell fate during lineage differentiation is a poorly understood phenomenon despite its ubiquity in multicellular organisms. We recently used a cell fusion assay to define a...
6.
Foshay K, Gallicano G
Dev Biol
. 2008 Dec;
326(2):431-43.
PMID: 19073166
MicroRNAs are small non-coding RNAs that regulate protein expression by binding 3'UTRs of target mRNAs, thereby inhibiting translation. Similar to siRNAs, miRNAs are cleaved by Dicer. Mouse and ES cell...
7.
Foshay K, Gallicano G
Stem Cells Dev
. 2008 May;
17(2):269-78.
PMID: 18447642
STAT3, a member of the signal transducer and activator or transcription (STAT) family of proteins, plays a major role in gliogenesis; however, its functions during differentiation of neural precursor cells...
8.
Foshay K, Gallicano G
Curr Stem Cell Res Ther
. 2008 Jan;
2(4):264-71.
PMID: 18220910
MicroRNAs (miRNAs) are a newly discovered, yet powerful mechanism for regulating protein expression via mRNA translational inhibition. Loss of all miRNA function within mice leads to embryonic lethality with a...