Jedidiah Gaetz
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Explore the profile of Jedidiah Gaetz including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
428
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Recent Articles
1.
Looney T, Zhang L, Chen C, Lee J, Chari S, Mao F, et al.
Genome Res
. 2013 Dec;
24(2):267-80.
PMID: 24310002
Both diffusible factors acting in trans and chromatin components acting in cis are implicated in gene regulation, but the extent to which either process causally determines a cell's transcriptional identity...
2.
Foshay K, Looney T, Chari S, Mao F, Lee J, Zhang L, et al.
Mol Cell
. 2012 Mar;
46(2):159-70.
PMID: 22445485
It is a long-held paradigm that cell fusion reprograms gene expression but the extent of reprogramming and whether it is affected by the cell types employed remain unknown. We recently...
3.
Gaetz J, Clift K, Fernandes C, Mao F, Lee J, Zhang L, et al.
Cell Res
. 2011 Nov;
22(5):848-58.
PMID: 22124232
The progressive restriction of cell fate during lineage differentiation is a poorly understood phenomenon despite its ubiquity in multicellular organisms. We recently used a cell fusion assay to define a...
4.
Lee J, Gaetz J, Bugarija B, Fernandes C, Snyder G, Bush E, et al.
Hum Mol Genet
. 2009 Apr;
18(14):2567-74.
PMID: 19380460
We recently described two opposing states of transcriptional competency. One is termed 'competent' whereby a gene is capable of responding to trans-acting transcription factors of the cell, such that it...
5.
Itabashi T, Takagi J, Shimamoto Y, Onoe H, Kuwana K, Shimoyama I, et al.
Nat Methods
. 2009 Jan;
6(2):167-72.
PMID: 19151719
Accurate chromosome segregation during meiosis depends on the assembly of a microtubule-based spindle of proper shape and size. Current models for spindle-size control focus on reaction diffusion-based chemical regulation and...
6.
Lee J, Bugarija B, Millan E, Walton N, Gaetz J, Fernandes C, et al.
Hum Mol Genet
. 2008 Dec;
18(5):835-46.
PMID: 19050040
A gene's transcriptional output is the combined product of two inputs: diffusible factors in the cellular milieu acting in trans, and chromatin state acting in cis. Here, we describe a...
7.
Yang G, Houghtaling B, Gaetz J, Liu J, Danuser G, Kapoor T
Nat Cell Biol
. 2007 Oct;
9(11):1233-42.
PMID: 17934454
Bipolarity of the meiotic spindle, required for proper chromosome segregation, is maintained throughout cell division despite rapid microtubule turnover. How this is achieved has remained mysterious, as determining the organization...
8.
Gaetz J, Gueroui Z, Libchaber A, Kapoor T
Nat Cell Biol
. 2006 Aug;
8(9):924-32.
PMID: 16892054
During cell division, the proper assembly of a microtubule-based bipolar spindle depends on signals from chromatin. However, it is unknown how the spatial organization of chromatin signals affects spindle morphology....
9.
Solecki D, Model L, Gaetz J, Kapoor T, Hatten M
Nat Neurosci
. 2004 Oct;
7(11):1195-203.
PMID: 15475953
Neuronal migrations along glial fibers provide a primary pathway for the formation of cortical laminae. To examine the mechanisms underlying glial-guided migration, we analyzed the dynamics of cytoskeletal and signaling...
10.
Gaetz J, Kapoor T
J Cell Biol
. 2004 Aug;
166(4):465-71.
PMID: 15314063
During cell division metaphase spindles maintain constant length, whereas spindle microtubules continuously flux polewards, requiring addition of tubulin subunits at microtubule plus-ends, polewards translocation of the microtubule lattice, and removal...