Kara L McKinley
Overview
Explore the profile of Kara L McKinley including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
926
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
McKinley K, Castillo-Azofeifa D, Klein O
Cell Stem Cell
. 2020 May;
26(5):632-656.
PMID: 32386555
Defining the mechanisms that generate specialized cell types and coordinate their functions is critical for understanding organ development and renewal. New tools and discoveries are challenging and refining our definitions...
12.
Rodriguez-Rodriguez J, Lewis C, McKinley K, Sikirzhytski V, Corona J, Maciejowski J, et al.
Curr Biol
. 2018 Nov;
28(21):3422-3429.e5.
PMID: 30415700
The Mad1-Mad2 heterodimer is the catalytic hub of the spindle assembly checkpoint (SAC), which controls M phase progression through a multi-subunit anaphase inhibitor, the mitotic checkpoint complex (MCC) [1, 2]....
13.
McKinley K, Stuurman N, Royer L, Schartner C, Castillo-Azofeifa D, Delling M, et al.
Elife
. 2018 Jun;
7.
PMID: 29897330
Cell division is essential to expand, shape, and replenish epithelia. In the adult small intestine, cells from a common progenitor intermix with other lineages, whereas cell progeny in many other...
14.
McKinley K
Methods Cell Biol
. 2018 May;
144:75-105.
PMID: 29804684
The faithful execution of cell division requires the coordinated action of hundreds of gene products. Precisely perturbing these gene products in cells is central to understanding their functions during normal...
15.
Guo L, Allu P, Zandarashvili L, McKinley K, Sekulic N, Dawicki-McKenna J, et al.
Nat Commun
. 2017 Jun;
8:15775.
PMID: 28598437
Maintaining centromere identity relies upon the persistence of the epigenetic mark provided by the histone H3 variant, centromere protein A (CENP-A), but the molecular mechanisms that underlie its remarkable stability...
16.
McKinley K, Cheeseman I
Dev Cell
. 2017 Feb;
40(4):405-420.e2.
PMID: 28216383
Defining the genes that are essential for cellular proliferation is critical for understanding organismal development and identifying high-value targets for disease therapies. However, the requirements for cell-cycle progression in human...
17.
McKinley K, Sekulic N, Guo L, Tsinman T, Black B, Cheeseman I
Mol Cell
. 2015 Dec;
60(6):886-98.
PMID: 26698661
During mitosis, the macromolecular kinetochore complex assembles on the centromere to orchestrate chromosome segregation. The properties and architecture of the 16-subunit Constitutive Centromere-Associated Network (CCAN) that allow it to build...
18.
McKinley K, Cheeseman I
Nat Rev Mol Cell Biol
. 2015 Nov;
17(1):16-29.
PMID: 26601620
The centromere is the region of the chromosome that directs its segregation in mitosis and meiosis. Although the functional importance of the centromere has been appreciated for more than 130...
19.
McKinley K, Cheeseman I
Cell
. 2014 Jul;
158(2):397-411.
PMID: 25036634
To ensure the stable transmission of the genome during vertebrate cell division, the mitotic spindle must attach to a single locus on each chromosome, termed the centromere. The fundamental requirement...
20.
Thiru P, Kern D, McKinley K, Monda J, Rago F, Su K, et al.
Mol Biol Cell
. 2014 May;
25(13):1983-94.
PMID: 24829384
The key player in directing proper chromosome segregation is the macromolecular kinetochore complex, which mediates DNA-microtubule interactions. Previous studies testing individual kinetochore genes documented examples of their overexpression in tumors...