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Kara L Marshall

Explore the profile of Kara L Marshall including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 967
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Recent Articles
1.
Hamed Y, Ghosh B, Marshall K
J Physiol . 2024 Mar; 602(19):4777-4788. PMID: 38456626
Many organs are designed to move: the heart pumps each second, the gastrointestinal tract squeezes and churns to digest food, and we contract and relax skeletal muscles to move our...
2.
Mulhall E, Gharpure A, Lee R, Dubin A, Aaron J, Marshall K, et al.
Nature . 2023 Aug; 620(7976):1117-1125. PMID: 37587339
PIEZOs are mechanosensitive ion channels that convert force into chemoelectric signals and have essential roles in diverse physiological settings. In vitro studies have proposed that PIEZO channels transduce mechanical force...
3.
Servin-Vences M, Lam R, Koolen A, Wang Y, Saade D, Loud M, et al.
Cell . 2023 Aug; 186(16):3386-3399.e15. PMID: 37541196
The gastrointestinal tract is in a state of constant motion. These movements are tightly regulated by the presence of food and help digestion by mechanically breaking down and propelling gut...
4.
Villarino N, Hamed Y, Ghosh B, Dubin A, Lewis A, Odem M, et al.
Neuron . 2023 Jun; 111(16):2488-2501.e8. PMID: 37321223
Sensory neurons detect mechanical forces from both the environment and internal organs to regulate physiology. PIEZO2 is a mechanosensory ion channel critical for touch, proprioception, and bladder stretch sensation, yet...
5.
Ma S, Dubin A, Romero L, Loud M, Salazar A, Chu S, et al.
Science . 2023 Jan; 379(6628):201-206. PMID: 36634173
Distal arthrogryposis (DA) is a collection of rare disorders that are characterized by congenital joint contractures. Most DA mutations are in muscle- and joint-related genes, and the anatomical defects originate...
6.
Marshall K, Saade D, Ghitani N, Coombs A, Szczot M, Keller J, et al.
Nature . 2020 Oct; 588(7837):290-295. PMID: 33057202
Henry Miller stated that "to relieve a full bladder is one of the great human joys". Urination is critically important in health and ailments of the lower urinary tract cause...
7.
Moayedi Y, Greenberg S, Jenkins B, Marshall K, Dimitrov L, Nelson A, et al.
Mol Carcinog . 2018 Dec; 58(5):722-734. PMID: 30582219
Bioactive derivatives from the camphor laurel tree, Cinnamomum camphora, are posited to exhibit chemopreventive properties but the efficacy and mechanism of these natural products are not fully understood. We tested...
8.
Zeng W, Marshall K, Min S, Daou I, Chapleau M, Abboud F, et al.
Science . 2018 Oct; 362(6413):464-467. PMID: 30361375
Activation of stretch-sensitive baroreceptor neurons exerts acute control over heart rate and blood pressure. Although this homeostatic baroreflex has been described for more than 80 years, the molecular identity of...
9.
Murthy S, Loud M, Daou I, Marshall K, Schwaller F, Kuhnemund J, et al.
Sci Transl Med . 2018 Oct; 10(462). PMID: 30305457
The brush of a feather and a pinprick are perceived as distinct sensations because they are detected by discrete cutaneous sensory neurons. Inflammation or nerve injury can disrupt this sensory...
10.
Marshall K, Clary R, Baba Y, Orlowsky R, Gerling G, Lumpkin E
Cell Rep . 2016 Nov; 17(7):1719-1727. PMID: 27829143
Sensory tissues exposed to the environment, such as skin, olfactory epithelia, and taste buds, continuously renew; therefore, peripheral neurons must have mechanisms to maintain appropriate innervation patterns. Although somatosensory neurons...